0000000000381302

AUTHOR

Ni Zeng

showing 1 related works from this author

BMP7 Gene involved in nonsyndromic orofacial clefts in western han Chinese

2015

Background: Nonsyndromic orofacial clefts (NSOCs) are the most common craniofacial birth defects with complex etiology in which multiple genes and environmental exposures are involved. Bone morphogenetic protein 7 (BMP7), as a member of the transforming growth factor-beta (TGF-beta) superfamily, has been shown to play crucial roles in palate and other orofacial ectodermal appendages development in animal models. Material and Methods: This study was designed to investigate the possible associations between BMP7 gene and the NSOCs (221 case-parent trios) in Western Han Chinese. Five tagSNPs at BMP7, rs12438, rs6099486, rs6127973, rs230188 and rs6025469 were picked and tried to cover the entir…

MaleBone Morphogenetic Protein 7Cleft LipGenetic counselingOdontologíaBiologyAsian PeopleHumansCraniofacialRisk factorAlleleGeneral DentistryGeneGeneticsOral Medicine and PathologyResearchBrainTransmission disequilibrium test:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludCleft PalateBone morphogenetic protein 7OtorhinolaryngologyUNESCO::CIENCIAS MÉDICASEtiologyFemaleSurgeryMedicina Oral Patología Oral y Cirugia Bucal
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