0000000000388216

AUTHOR

Grazia D'onofrio

showing 2 related works from this author

Enteral tube feeding and mortality in hospitalized older patients: A multicenter longitudinal study

2020

Background & aims: The literature regarding enteral nutrition and mortality in older frail people is limited and still conflicting. Moreover, the potential role of comprehensive geriatric assessment is poorly explored. We therefore aimed to investigate whether the Multidimensional Prognostic Index (MPI), an established tool that assesses measures of frailty and predicts mortality, may help physicians in identifying patients in whom ETF (enteral tube feeding) is effective in terms of reduced mortality. Methods: Observational, longitudinal, multicenter study with one year of follow-up. Data regarding ETF were recorded through medical records. A standardized comprehensive geriatric assessm…

Male0301 basic medicinemedicine.medical_specialtyLongitudinal studyPrognosis.030209 endocrinology & metabolismCritical Care and Intensive Care MedicineHospital03 medical and health sciences0302 clinical medicineMultidimensional prognostic indexOdds RatiomedicineRisk of mortalityHumansLongitudinal StudiesMortalityAgedEnteral Tube FeedingAged 80 and overInpatients030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryMedical recordAustraliaOdds ratioConfidence intervalEuropeParenteral nutritionEmergency medicinePropensity score matchingFemaleEnteral nutritionbusinessClinical Nutrition
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Acetylcholinesterase inhibitors are associated with weight loss in older people with dementia: A systematic review and meta-analysis

2016

We conducted a systematic review and meta-analysis investigating the influence of acetylcholinesterase inhibitors (AChEIs) therapy on nutritional status and weight across observational and interventional studies. Two authors searched major electronic databases from inception until 10/14/2015 for longitudinal, open-label and randomised double-blind placebo controlled (randomised controlled trials (RCTs)) studies of AChEIs in patients with dementia reporting nutritional status outcome data. Out of 3551 initial hits, 25 studies (12 open-label trials, 9 RCTs and 4 longitudinal studies) including 10 792 patients with dementia were meta-analysed. In longitudinal studies (median follow-up 6 months…

Malemedicine.medical_specialtyPlaceboRisk Assessment03 medical and health sciences0302 clinical medicineArts and Humanities (miscellaneous)Weight lossAlzheimer DiseaseInternal medicineWeight LossmedicineDementiaHumansCumulative incidence030212 general & internal medicineAgedRandomized Controlled Trials as TopicGeriatricsbusiness.industryDEMENTIAmedicine.diseaseMETA-ANALYSISALZHEIMER'S DISEASE; DEMENTIA; GERIATRICS; META-ANALYSIS; Neurology (clinical); Psychiatry and Mental Health; Surgery; Arts and Humanities (miscellaneous)Acetylcholinesterase inhibitorsALZHEIMER'S DISEASEPsychiatry and Mental HealthMeta-analysisPhysical therapyObservational studyFemaleSurgeryCholinesterase InhibitorsNeurology (clinical)medicine.symptombusinessOlder peopleGERIATRICS030217 neurology & neurosurgery
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