0000000000391006

AUTHOR

Hermann Toplak

showing 3 related works from this author

Obesity and cardiovascular risk

2018

: Obesity is a key factor for cardiovascular diseases and complications. Obesity is associated with hypertension, dyslipidemia and type II diabetes, which are the major predictors of cardiovascular disease in the future. It predisposes for atrial fibrillation, heart failure, sudden cardiac death, renal disease and ischemic stroke that are the main causes of cardiovascular hospitalization and mortality. As obesity and the cardiovascular effects on the vessels and the heart start early in life, even from childhood, it is important for health policies to prevent obesity very early before the disease manifestation emerge. Key roles in the prevention are strategies to increase physical exercise,…

cardiovascular riskobesitymedicine.medical_specialtyConsensushypertensionPhysiologyPhysical exerciseDiseaseType 2 diabetes030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineRisk FactorsDiabetes mellitusInternal MedicinemedicineHumansguidelines030212 general & internal medicineIntensive care medicineExerciseLife StyleStrokeDyslipidemiasdiabetesbusiness.industrydyslipidemiamedicine.diseaseObesityDiabetes Mellitus Type 2Cardiovascular DiseasesdiabeteHeart failureCardiology and Cardiovascular MedicinebusinessguidelineDyslipidemiaJournal of Hypertension
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Obesity and cardiovascular risk: a call for action from the European Society of Hypertension Working Group of Obesity, Diabetes and the High-risk Pat…

2018

: Obesity predisposes for atrial fibrillation, heart failure, sudden cardiac death, renal disease and ischemic stroke, which are the main causes of cardiovascular hospitalization and mortality. As obesity and the cardiovascular effects on the vessels and the heart start early in life, even from childhood, it is important for health policies to prevent obesity very early before the disease manifestation emerge. Key roles in the prevention are strategies to increase physical exercise, reduce body weight and to prevent or treat hypertension, lipids disorders and diabetes earlier and efficiently to prevent cardiovascular complications.

adolescent hypertensioncardiovascular riskmedicine.medical_specialtyBiomedical ResearchConsensusPhysiologyheart failurePhysical exerciseDisease030204 cardiovascular system & hematologysudden cardiac deathSudden cardiac death03 medical and health sciencesbody weight0302 clinical medicineRisk FactorsDiabetes mellitusWeight LossMetabolically healthy obesityDiabetes MellitusInternal MedicinemedicineHumansatrial fibrillation030212 general & internal medicineObesityIntensive care medicineExerciseStrokeDyslipidemiasdiabetesbusiness.industrydyslipidemiacardiorespiratory fitnemedicine.diseaseObesityStrokediabeteCardiovascular DiseasesHeart failureHypertensionmetabolically healthy obesityCardiology and Cardiovascular Medicinebusinesschronic kidney disease
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Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

2021

Background The European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (FHSC) global registry provides a platform for the global surveillance of familial hypercholesterolaemia through harmonisation and pooling of multinational data. In this study, we aimed to characterise the adult population with heterozygous familial hypercholesterolaemia and described how it is detected and managed globally. Methods Using FHSC global registry data, we did a cross-sectional assessment of adults (aged 18 years or older) with a clinical or genetic diagnosis of probable or definite heterozygous familial hypercholesterolaemia at the time they were entered into the registries. Dat…

MaleSettore MED/09 - Medicina InternaArterial diseaseCross-sectional studyAdult populationCoronary DiseaseDiseaseGlobal HealthMedical and Health SciencesDoenças Cardio e Cérebro-vascularesAnticholesteremic AgentMonoclonalPrevalenceRegistriesFamilial HypercholesterolemiaHumanizedStroke11 Medical and Health SciencesLS2_9Studies CollaborationAnticholesteremic AgentsGeneral MedicineHeart Disease Risk FactorMiddle AgedFHSC global registry dataEuropeTreatment OutcomeLower prevalenceGuidancelipids (amino acids peptides and proteins)FemaleProprotein Convertase 9Familial hypercholesterolaemiaLife Sciences & BiomedicineHumanAdultmedicine.medical_specialtyCombination therapyFHSC global registry heterozygous familial hypercholesterolaemiaCardiovascular risk factorsAntibodies Monoclonal HumanizedInsightsAntibodiesNOHyperlipoproteinemia Type IIClinicianMedicine General & InternalInternal medicineGeneral & Internal MedicineHealth SciencesmedicineHumansEAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)Cross-Sectional StudieScience & TechnologyGlobal Perspectivebusiness.industryCholesterol LDLmedicine.diseaseCross-Sectional StudiesHeart Disease Risk FactorsHydroxymethylglutaryl-CoA Reductase InhibitorHydroxymethylglutaryl-CoA Reductase Inhibitorsbusiness
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