0000000000394252

AUTHOR

Matteo Cortellari

showing 6 related works from this author

Runs of homozygosity in the Italian goat breeds: impact of management practices in low-input systems

2021

Abstract Background Climate and farming systems, several of which are considered as low-input agricultural systems, vary between goat populations from Northern and Southern Italy and have led to different management practices. These processes have impacted genome shaping in terms of inbreeding and regions under selection and resulted in differences between the northern and southern populations. Both inbreeding and signatures of selection can be pinpointed by the analysis of runs of homozygosity (ROH), which provides useful information to assist the management of this species in different rural areas. Results We analyzed the ROH distribution and inbreeding (FROH) in 902 goats from the Italia…

adaptation; body size; climate change; ecological impact; farming system; goat; inbreeding; management practiceClimateecological impactadaptationQH426-470Runs of homozygosityPolymorphism Single NucleotideSF1-1100GeneticsAnimalsfarming systemsInbreedingPolymorphismEcology Evolution Behavior and SystematicsbiodiversityGenomeSettore AGR/17 - ZOOTECNICA GENERALE E MIGLIORAMENTO GENETICOlocal breedsAnimalGoatsROHHomozygoteGeneral MedicineSingle NucleotideAnimal cultureclimate changeAnimals; Genome; Homozygote; Inbreeding; Goats; Polymorphism Single Nucleotidelocal breeds biodiversity SNPs inbreedingGoatfarming systemRuns of homozygosity ROH Goat signatures of selection low-input system Climate farming systemsAnimal Science and Zoologybody sizeGoat signatures of selectionlow-input systemmanagement practiceResearch ArticleSNPs
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Additional file 2 of Runs of homozygosity in the Italian goat breeds: impact of management practices in low-input systems

2021

Additional file 2: Figure S2. Manhattan plots representing the signals of signatures of selection in the two population groups (CSD and NRD), of the ��ROH, and averaged FST. CSD = Central-southern population group; NRD = Northern population group.

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Genome-Wide Patterns of Homozygosity Reveal the Conservation Status in Five Italian Goat Populations.

2021

The application of genomic technologies has facilitated the assessment of genomic inbreeding based on single nucleotide polymorphisms (SNPs). In this study, we computed several runs of homozygosity (ROH) parameters to investigate the patterns of homozygosity using Illumina Goat SNP50 in five Italian local populations: Argentata dell’Etna (N = 48), Derivata di Siria (N = 32), Girgentana (N = 59), Maltese (N = 16) and Messinese (N = 22). The ROH results showed well-defined differences among the populations. A total of 3687 ROH segments &gt

Genetic diversityruns of homozygosityGeneral Veterinarygenomic regions.Veterinary medicinePopulation sizeinbreedingSingle-nucleotide polymorphismPhenotypic traitBiologyRuns of Homozygositylocal goat populationBreedArticleGene flowQL1-991Evolutionary biologylocal goat populationsSF600-1100Animal Science and Zoologygenomic regionsZoologyInbreedingGenomic regions; Inbreeding; Local goat populations; Runs of homozygosityAnimals : an open access journal from MDPI
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The climatic and genetic heritage of Italian goat breeds with genomic SNP data

2021

Local adaptation of animals to the environment can abruptly become a burden when faced with rapid climatic changes such as those foreseen for the Italian peninsula over the next 70 years. Our study investigates the genetic structure of the Italian goat populations and links it with the environment and how genetics might evolve over the next 50 years. We used one of the largest national datasets including > 1000 goats from 33 populations across the Italian peninsula collected by the Italian Goat Consortium and genotyped with over 50 k markers. Our results showed that Italian goats can be discriminated in three groups reflective of the Italian geography and its geo-political situation prec…

GenotypePopulation geneticsGoat conservationScienceAnimals; Genetics Population; Genomics; Genotype; Goats; Polymorphism Single Nucleotide; Selection GeneticPopulationadaptationArticleClimate Change goat SNPs Goat conservation Goat GeneticsGeneticAnimals; Genetics Population; Genotype; Selection Genetic; Genomics; Goats; Polymorphism Single NucleotideGeneticsAnimalsPolymorphismSelectionSettore AGR/17 - ZOOTECNICA GENERALE E MIGLIORAMENTO GENETICOlocal breedsGoatsQgoatRBiodiversityGoat GeneticsGenomicsSingle NucleotideGoat local breeds SNPs adaptation population structureclimate changeHaplotypeslocal breeds goat genomic analysis climate changegenomic analysisMedicineSNPs
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Additional file 1 of Runs of homozygosity in the Italian goat breeds: impact of management practices in low-input systems

2021

Additional file 1: Figure S1. Geographic distribution (a), phylogeny tree (b), and multidimensional scaling analysis (c) of all the Italian goat breeds included in the study.

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Additional file 3 of Runs of homozygosity in the Italian goat breeds: impact of management practices in low-input systems

2021

Additional file 3: Table S1. List of the genes identified by the analyses of the signatures of selection: top 1% homozygosity score in CSD and NRD groups, ��ROH, and averaged FST. CSD = Central-southern population group; NRD = Northern population group.

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