0000000000395066
AUTHOR
A.m. García
Community response to environmental noise in Valencia
Abstract In Valencia, Spain, 263 residents were interviewed at five different locations in order to investigate the subjective response to environmental noise in urban areas. External noise levels were measured over five consecutive days at each site. Noise levels were high in two of the selected sites ( L eq 24h about 75 dBA) and lower in the other two ( L eq 24h about 65 dBA). The fifth location had a night noise problem because of the presence of many leisure places (pubs, restaurants, etc.). The scores of the sample with their satisfaction with their neighbourhood were notably higher in the quiet than in the noisy areas (83% and 64% respectively). Road traffic and pub noise (in the fift…
Association between M467T and 114 C--A variants within the SLC3A1 gene and some phenotypical traits in cystinuria patients from Spain.
Cystinuria is an inherited metabolic disease characterized by an abnormal urinary excretion of cystine and dibasic amino acids. Formation of renal calculi, recurrent infections and renal failure are the main complications of this disease. The SLC3A1 gene, which codes for a dibasic amino acid transporter protein, is involved in the pathogenesis of cystinuria. We investigated the possible association between molecular variants (M467T, E483X, T216 M and 114 C--A) within the SLC3A1 gene and some phenotypical traits in a Spanish area. The study population consisted of 45 cystinuria patients, 42 cystinuria relatives and 81 healthy control subjects. Only the M467T mutation was found in chromosomes…