0000000000395679

AUTHOR

Oguzhan Gunduz

0000-0002-9427-7574

showing 2 related works from this author

Propolis-Based Nanofiber Patches to Repair Corneal Microbial Keratitis

2021

In this research, polyvinyl-alcohol (PVA)/gelatin (GEL)/propolis (Ps) biocompatible nanofiber patches were fabricated via electrospinning technique. The controlled release of Propolis, surface wettability behaviors, antimicrobial activities against the S. aureus and P. aeruginosa, and biocompatibility properties with the mesenchymal stem cells (MSCs) were investigated in detail. By adding 0.5, 1, and 3 wt.% GEL into the 13 wt.% PVA, the morphological and mechanical results suggested that 13 wt.% PVA/0.5 wt.% GEL patch can be an ideal matrix for 3 and 5 wt.% propolis addition. Morphological results revealed that the diameters of the electrospun nanofiber patches were increased with GEL (from…

Pharmaceutical ScienceBiocompatible Materials02 engineering and technologyGelatinAnalytical ChemistryContact angleQD241-4410302 clinical medicineAnti-Infective AgentsSpectroscopy Fourier Transform InfraredDrug DiscoveryMesenchymal stem cell proliferationDrug CarriersChemistrySSCAFFOLDHYDROGELP<i>S. aureus</i>021001 nanoscience & nanotechnologyControlled releaseaeruginosaElectrospinningpropolisChemistry (miscellaneous)microbial keratitisPseudomonas aeruginosaBLINDNESSMolecular MedicineELECTROSPUN0210 nano-technologyStaphylococcus aureusfood.ingredient<i>P. aeruginosa</i>BiocompatibilitySurface PropertiesFABRICATIONMicrobial Sensitivity TestsCHEMICAL-COMPOSITIONaureusArticle03 medical and health sciencesfoodnanofibersPhysical and Theoretical Chemistrycorneal patchelectrospinningKeratitisCOMPOSITEGELATINOrganic ChemistryPropolisS. aureusDrug LiberationP. aeruginosaPolyvinyl AlcoholNanofiber030221 ophthalmology & optometryPROPERTYMEMBRANENuclear chemistry
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Controlled Release of Metformin Hydrochloride from Core-Shell Nanofibers with Fish Sarcoplasmic Protein

2019

Ficai, Anton/0000-0002-1777-0525; Karademir, Betul/0000-0003-1762-0284 WOS:000503463400074 PubMed ID: 31658758 Background and Objectives: A coaxial electrospinning technique was used to produce core/shell nanofibers of a polylactic acid (PLA) as a shell and a polyvinyl alcohol (PVA) containing metformin hydrochloride (MH) as a core. Materials and Methods: Fish sarcoplasmic protein (FSP) was extracted from fresh bonito and incorporated into nanofiber at various concentrations to investigate the influence on properties of the coaxial nanofibers. The morphology, chemical structure and thermal properties of the nanofibers were studied. Results: The results show that uniform and bead-free struct…

Medicine (General)POLYMERIC NANOFIBERSChemical structurewound healingIn Vitro Techniquescoaxial electrospinningPolyvinyl alcoholArticleDELIVERYCrystallinitychemistry.chemical_compoundcoaxial electrospinning; fish sarcoplasmic protein; nanofibers; wound healingR5-920Differential scanning calorimetryPolylactic acidnanofibersSpectroscopy Fourier Transform InfraredMedicineAnimalsbusiness.industryTunaGeneral MedicineControlled releaseMetforminfish sarcoplasmic proteinDrug LiberationSarcoplasmic ReticulumchemistryChemical engineeringNanofiberDelayed-Action PreparationsPolyvinyl AlcoholELECTROSPUN NANOFIBERSCoaxialbusinessFIBERSMATRICES
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