0000000000395725

AUTHOR

Alessandro Larcher

showing 3 related works from this author

Prediction of significant renal function decline after open, laparoscopic, and robotic partial nephrectomy: External validation of the Martini’s nomo…

2022

Objectives: Martini et al. developed a nomogram to predict significant (>25%) renal function loss after robot-assisted partial nephrectomy and identified four risk categories. We aimed to externally validate Martini’s nomogram on a large, national, multi-institutional data set including open, laparoscopic, and robot-assisted partial nephrectomy. Methods: Data of 2584 patients treated with partial nephrectomy for renal masses at 26 urological Italian centers (RECORD2 project) were collected. Renal function was assessed at baseline, on third postoperative day, and then at 6, 12, 24, and 48 months postoperatively. Multivariable models accounting for variables included in the Martini’s nomog…

laparoscopy; nephron-sparing surgery; renal cell carcinoma; renal function; robotics; Humans; Kidney; Nephrectomy; Nomograms; Kidney Neoplasms; Laparoscopy; Robotic Surgical Procedures; Roboticsroboticsrenal cell carcinomaUrologyrenal functionlaparoscopynephron-sparing surgeryKidneyNephrectomyKidney NeoplasmsNomogramsRobotic Surgical ProceduresHumansLaparoscopyrobotics.Laparoscopy; nephron-sparing surgery; renal cell carcinoma; renal function; robotics.International Journal of Urology
researchProduct

Transperitoneal vs retroperitoneal minimally invasive partial nephrectomy: comparison of perioperative outcomes and functional follow-up in a large m…

2020

Abstract Background Aim of this study was to evaluate and compare perioperative outcomes of transperitoneal (TP) and retroperitoneal (TR) approaches in a multi-institutional cohort of minimally invasive partial nephrectomy (MI-PN). Material and methods All consecutive patients undergone MI-PN for clinical T1 renal tumors at 26 Italian centers (RECORd2 project) between 01/2013 and 12/2016 were evaluated, collecting the pre-, intra-, and postoperative data. The patients were then stratified according to the surgical approach, TP or RP. A 1:1 propensity score (PS) matching was performed to obtain homogeneous cohorts, considering the age, gender, baseline eGFR, surgical indication, clinical dia…

medicine.medical_specialtyIntraoperative ComplicationUrologymedicine.medical_treatmentOperative TimeSurgical approach030232 urology & nephrologyMinimally invasive partial nephrectomy Renal cell carcinoma Retroperitoneal Surgical approach Transperitoneal.lcsh:RC870-923lcsh:RC254-282NephrectomyArticle03 medical and health sciences0302 clinical medicineRenal cell carcinomamedicineMinimally invasive partial nephrectomy; Renal cell carcinoma; Retroperitoneal; Surgical approach; TransperitonealHumansRetroperitoneal SpaceRetrospective StudiesMinimally invasive partial nephrectomybusiness.industryRenal cell carcinoma; Minimally invasive partial nephrectomy; Transperitoneal; Retroperitoneal; Surgical approachTransperitonealPerioperativeRetroperitoneallcsh:Diseases of the genitourinary system. Urologylcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseNephrectomyKidney NeoplasmsRenal cell carcinomaSurgerySettore MED/24Treatment Outcome030220 oncology & carcinogenesisPropensity score matchingCohortSurgeryLaparoscopyPositive Surgical MarginMinimally invasive partial nephrectomy; Renal cell carcinoma; Retroperitoneal; Surgical approach; Transperitoneal; Follow-Up Studies; Humans; Nephrectomy; Operative Time; Retroperitoneal Space; Retrospective Studies; Treatment Outcome; Kidney Neoplasms; LaparoscopybusinessAbdominal surgeryFollow-Up StudiesSurgical endoscopy
researchProduct

Predicting positive surgical margins in partial nephrectomy: A prospective multicentre observational study (the RECORd 2 project)

2020

PURPOSE: to evaluate clinical predictors of positive surgical margins (PSMs) in a large multicenter prospective observational study and to develop a clinic nomogram to predict the likelihood of PSMs after partial nephrectomy (PN). MATERIALS AND METHODS: We prospectively evaluated 4308 patients who had surgical treatment for renal tumors between January 2013 and December 2016 at 26 urological Italian Centers (RECORd 2 project). Two multivariable logistic models were evaluated to predict the likelihood of PSMs. Center caseload was dichotomized using a visual assessment adjusted for several predictors of PSMs. A nomogram predicting PSMs was developed. RESULTS: Overall, 2076 patients treated wi…

MaleNeoplasm ResidualDatabases Factualmulticenter prospective observational studymedicine.medical_treatment030232 urology & nephrologyNephron-sparing surgeryNephrectomyNomogram0302 clinical medicineRenal cell carcinomaRisk Factorsclinical predictorPartial nephrectomyProspective StudiesStage (cooking)Prospective cohort studySurgical margins Nephron-sparing surgery Nomogram Partial nephrectomy Renal cell carcinoma Robot-assisted partial nephrectomySurgical marginsRobot-assisted partial nephrectomyMargins of ExcisionGeneral MedicineMiddle AgedNephrectomyKidney NeoplasmsHospitalsRenal cell carcinomaOncologyElective Surgical Procedures030220 oncology & carcinogenesisArea Under CurveResidualNephron-sparing surgery; Nomogram; Partial nephrectomy; Renal cell carcinoma; Robot-assisted partial nephrectomy; Surgical marginsFemalepositive surgical marginPositive Surgical MarginElective Surgical Proceduremedicine.medical_specialtyHospitals Low-VolumeHigh-Volume03 medical and health sciencesDatabasesSurgical margins; Nephron-sparing surgery; Nomogram; Partial nephrectomy; Renal cell carcinoma; Robot-assisted partial nephrectomyInternal medicineLow-VolumemedicineHumansNeoplasm InvasivenessCarcinoma Renal CellFactualAgedNeoplasm Stagingbusiness.industryCarcinomaRenal CellNomogrammedicine.diseaseNomogramsSettore MED/24Logistic ModelsROC CurveNeoplasmSurgeryObservational studybusinessHospitals High-Volume
researchProduct