0000000000396226

AUTHOR

Daniel Burkhoff

showing 2 related works from this author

Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg

1990

0303 health sciencesPhysiologyChemistryClinical BiochemistryTibialis AnteriorHuman physiology030204 cardiovascular system & hematologyPharmacologySpring (mathematics)ArticleAtrial Natriuretic Peptide03 medical and health sciences0302 clinical medicineAtrial natriuretic peptidePhysiology (medical)Spreading DepressionCapsaicinExtensor Digitorum Longus030304 developmental biologyPflugers Archiv
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Pacemaker-Based Cardiac Neuromodulation Therapy in Patients With Hypertension: A Pilot Study.

2021

Background In prior unblinded studies, cardiac neuromodulation therapy (CNT) employing a sequence of variably timed short and longer atrioventricular intervals yielded sustained reductions of systolic blood pressure (SBP) in patients with hypertension. The effects of CNT on SBP were investigated in this double‐blind randomized pilot study. Methods and Results Eligible patients had daytime ambulatory SBP (aSBP) ≥130 mm Hg and office SBP ≥140 mm Hg despite taking ≥1 antihypertensive medication, and an indication for a dual‐chamber pacemaker. Patients underwent Moderato device implantation, which was programmed as a standard pacemaker during a 1‐month run‐in phase. Patients whose daytime aSBP…

Malemedicine.medical_specialtyPacemaker ArtificialTime Factorshypertensionatrioventricular interval ; hypertension ; left ventricular function ; pacemakerBlood PressurePilot ProjectsArrhythmiasVentricular Function LeftDouble-Blind MethodHeart RateInternal medicineMedicineHumansIn patientProspective StudiesSequence (medicine)AgedOriginal ResearchAged 80 and overbusiness.industryCardiac Pacing ArtificialEditorialsHeartNeuromodulation (medicine)EuropeTreatment OutcomeEditorialCardiologyFemaleCardiology and Cardiovascular Medicinebusinesshigh blood pressureJournal of the American Heart Association
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