0000000000397375

AUTHOR

Ioanna Antoniadou

showing 1 related works from this author

Polymorphisms in ABC transporter genes and concentrations of mercury in newborns - Evidence from two Mediterranean birth cohorts

2014

Background: The genetic background may influence methylmercury (MeHg) metabolism and neurotoxicity. ATP binding cassette (ABC) transporters actively transport various xenobiotics across biological membranes. Objective: To investigate the role of ABC polymorphisms as modifiers of prenatal exposure to MeHg. Methods: The study population consisted of participants (n = 1651) in two birth cohorts, one in Italy and Greece (PHIME) and the other in Spain (INMA). Women were recruited during pregnancy in Italy and Spain, and during the perinatal period in Greece. Total mercury concentrations were measured in cord blood samples by atomic absorption spectrometry. Maternal fish intake during pregnancy w…

Fetus -- CreixementMaternal HealthEmbaràsEnvironmental Health and Occupational Healthlcsh:MedicinePhysiologyATP-binding cassette transporterSangToxicologyHeavy MetalsBiochemistryCohort Studieschemistry.chemical_compoundGene FrequencyPregnancySurveys and QuestionnairesGenotypeMedicine and Health SciencesToxinslcsh:ScienceMethylmercuryGeneticsMultidisciplinaryGreeceObstetrics and GynecologyFetal BloodMultidrug Resistance-Associated Protein 23. Good healthChemistryItalyMaternal ExposureResearch DesignCord bloodBlood ChemistryPhysical SciencesPopulation studyFemaleEpigeneticsResearch ArticleAdultNeurotoxicologyPollutantsGenotypeClinical Research DesignToxic AgentsSingle-nucleotide polymorphismBiologyResearch and Analysis MethodsYoung AdultFish ProductsGeneticsmedicineHumansEnvironmental ChemistryAllele frequencyNutritionEvolutionary BiologyPregnancyPolymorphism GeneticPopulation Biologylcsh:RInfant NewbornBiology and Life SciencesComputational BiologyHuman GeneticsMercurymedicine.diseasechemistrySpainGenetic PolymorphismWomen's HealthATP-Binding Cassette Transporterslcsh:QPopulation Genetics
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