0000000000400253

AUTHOR

Inéz Frerichs

showing 6 related works from this author

Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: Study protocol for a pilot randomized controlled trial, the PROT…

2018

Background Adding cyclic short sustained inflations (sigh) to assisted ventilation yields optimizes lung recruitment, decreases heterogeneity and reduces inspiratory effort in patients with acute hypoxemic respiratory failure (AHRF). These findings suggest that adding sigh to pressure support ventilation (PSV) might decrease the risk of lung injury, shorten weaning and improve clinical outcomes. Thus, we conceived a pilot trial to test the feasibility of adding sigh to PSV (the PROTECTION study). Methods PROTECTION is an international randomized controlled trial that will be conducted in 23 intensive care units (ICUs). Patients with AHRF who have been intubated from 24 h to 7 days and under…

procedurePressure supportTime Factorsgenetic structuresbreathingmedicine.medical_treatmentMedicine (miscellaneous)Pilot Projects[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractintensive care unitlaw.inventionPositive-Pressure RespirationStudy Protocol0302 clinical medicineMechanical ventilationRandomized controlled triallawtime factorClinical endpointpatient safetyMulticenter Studies as TopicPharmacology (medical)030212 general & internal medicinerandomized controlled trial (topic)Intervention study; Mechanical ventilation; Positive-pressure ventilation; Pressure support; Recruitment; Sigh; Ventilator-induced lung injury; Weaning; Feasibility Studies; Humans; Hypoxia; Intubation Intratracheal; Lung; Multicenter Studies as Topic; Pilot Projects; Positive-Pressure Respiration; Recovery of Function; Respiratory Insufficiency; Time Factors; Treatment Outcome; Randomized Controlled Trials as Topic; Medicine (miscellaneous); Pharmacology (medical)HypoxiaLungpathophysiologyendotracheal intubationRandomized Controlled Trials as TopicVentilator-induced lung injurylcsh:R5-920Intervention studyadultpilot studyfeasibility studytreatment outcome Feasibility Studie3. Good healthTreatment OutcomeAnesthesiapositive end expiratory pressureBreathingmulticenter study (topic)oxygenationRecruitmentlcsh:Medicine (General)Respiratory Insufficiencyrespiratory tract intubationcirculatory and respiratory physiologyHumanextubationPressure support ventilationWeaningLung injuryArticleSpontaneous breathing trialNO03 medical and health sciencesIntensive care[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]medicineIntubation IntratrachealHumanscontrolled studyPilot ProjectSightreatment failureMechanical ventilationhypoxemiapressure support ventilationtreatment durationbusiness.industrylung inflationrespiratory failureconvalescenceRecovery of Functionmajor clinical studymortalitywater acute respiratory failurehospital dischargeIntratracheal030228 respiratory systemrandomized controlled trialFeasibility StudiesbusinessPositive-pressure ventilationIntubationclinical protocol
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Heterogeneity Of Lung Ventilation In COPD Patients And Healthy Adults Determined By Electrical Impedance Tomography

2011

medicine.medical_specialtybusiness.industryCopd patientsInternal medicinemedicineCardiologyIntensive care medicinebusinessLung ventilationElectrical impedance tomographyC44. COPD: NOVEL DIAGNOSTIC TOOLS
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Chest electrical impedance tomography examination, data analysis, terminology, clinical use and recommendations: consensus statement of the translati…

2017

Electrical impedance tomography (EIT) has undergone 30 years of development. Functional chest examinations with this technology are considered clinically relevant, especially for monitoring regional lung ventilation in mechanically ventilated patients and for regional pulmonary function testing in patients with chronic lung diseases. As EIT becomes an established medical technology, it requires consensus examination, nomenclature, data analysis and interpretation schemes. Such consensus is needed to compare, understand and reproduce study findings from and among different research groups, to enable large clinical trials and, ultimately, routine clinical use. Recommendations of how EIT findi…

Lung DiseasesPathologyPulmonary CirculationLungeTerminologyPaediatric Lung Disaese0302 clinical medicineElectric ImpedanceMedicine1506Medical diagnosisCardiac OutputChildTomographyddc:618Lung Diseases/diagnostic imaging/physiopathology/therapyRespirationHealth technology3. Good healthChild PreschoolArtificialElectrical Impedance Tomography (EIT)Pulmonary and Respiratory MedicineAdultmedicine.medical_specialtyConsensusAssisted VentilationAdolescentTherapy planningImaging/CT MRI etcMedizintechnik03 medical and health sciencesTerminology as TopicState of the Art ReviewHumansMedical physicsIn patientddc:610PreschoolElectrical impedance tomographyStatement (computer science)business.industryInfant NewbornInfant030208 emergency & critical care medicineTOMOGRAFIA COMPUTADORIZADA POR RAIOS XNewbornRespiration ArtificialClinical trial030228 respiratory systemElektrische Impedanz-Tomografie (EIT)ARDSbusinessTomography/methods
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The Effect Of Automatic Weaning Using Smartcare/ps On Health-Related Quality Of Life

2011

Health related quality of lifebusiness.industryEnvironmental healthWeaningMedicinebusinessB50. MECHANICAL VENTILATION: NONINVASIVE VENTILATION AND WEANING
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High-Frequency Oscillatory Ventilation In Patients With Chronic Obstructive Pulmonary Disease

2011

medicine.medical_specialtybusiness.industryInternal medicineCardiologymedicinePulmonary diseaseIn patientbusinessHigh frequency oscillatory ventilationA48. CLINICAL RESEARCH
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Ventilation Distribution In Two Different Models Of Acute Lung Injury - Electrical Impedance Tomography Validation By Dynamic Xenon-Multidetector-Row…

2011

medicine.medical_specialtymedicine.diagnostic_testbusiness.industrychemistry.chemical_elementComputed tomographyLung injurylaw.inventionXenonchemistrylawVentilation (architecture)medicineDistribution (pharmacology)RadiologybusinessElectrical impedance tomographyD31. NON-PULMONARY CRITICAL CARE AND MONITORING
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