0000000000400588
AUTHOR
Nan Zhang
showing 4 related works from this author
Staphylococcus aureusand its IgE-inducing enterotoxins in asthma: current knowledge
2020
While immunoglobulin (Ig) E is a prominent biomarker for early-onset, its levels are often elevated in non-allergic late-onset asthma. However, the pattern of IgE expression in the latter is mostly polyclonal, with specific IgEs low or below detection level albeit with an increased total IgE. In late-onset severe asthma patients, specific IgE to Staphylococcal enterotoxins (se-IgE) can frequently be detected in serum, and has been associated with asthma, with severe asthma defined by hospitalisations, oral steroid use and decrease in lung function. Recently,se-IgE was demonstrated to even predict the development into severe asthma with exacerbations over the next decade.Staphylococcus aureu…
Dual-process Accounts of Reasoning in User's Information System Risky Behavior
2016
End user of information system (IS) is the weakest point in terms of IS security. A variety of approaches are developed to convince end users to avoid IS risky behaviors. However, they do not always work. We would like to argue that one of the reasons is that previous studies focused on System 2 thinking (analytic, deliberate, rule-governed and effortful process) and overlooked the factors that can influence people who are using System 1 thinking (automatic, effortless, associative and intuitive process). In this study, we propose a model that integrates influential factors for both modes of thinking together. Moderators of such relationships will be discussed as well. A laboratory experime…
Network Overlap and Network Blurring in Online Social Networks
2016
Online communities and the online social networks embedded become a prominent medium for social interactions. The success of social media depends on usersâ willingness to continue investing their time and efforts in the absence of economic rewards, making psychological attachment critical to online communities. While prior studies identify that members do develop psychological commitment to online communities, why and how the commitment arises remain underexplored. This study focuses on the relationship between network overlap, a common feature of online social networks, and affective commitment to an online community. Drawing on the commitment theory and social network boundary theory, w…
Specific IgE against Staphylococcus aureus enterotoxins: an independent risk factor for asthma.
2012
The role of IgE in patients with severe asthma is not fully understood.We sought to investigate whether IgE to Staphylococcus aureus enterotoxins might be relevant to disease severity in adult asthmatic patients.Specific IgE antibody concentrations in serum against enterotoxins, grass pollen (GP), and house dust mite allergens and total IgE levels were measured in adult cohorts of 69 control subjects, 152 patients with nonsevere asthma, and 166 patients with severe asthma. Severe asthma was defined as inadequately controlled disease despite high-dose inhaled corticosteroids plus at least 2 other controller therapies, including oral steroids.Enterotoxin IgE positivity was significantly great…