0000000000403913

AUTHOR

Donata Gellrich

showing 2 related works from this author

Is Quantitative sIgE Serology Suitable for Distinguishing Between Silent Sensitization and Allergic Rhinitis to Dermatophagoides pteronyssinus?

2019

BACKGROUND AND OBJECTIVE An increasing number of studies have recently discussed whether provocation tests might be replaced by specific IgE serology in patients sensitized to airborne allergens. Objective: Our study aimed to analyze the concordance between a nasal provocation test with Dermatophagoides pteronyssinus and specific IgE measurements based on real-life data. METHODS We retrospectively analyzed concordance between the result of the provocation test and the IgE titer for house dust mite components and extracts in 223 patients with proven sensitization to D pteronyssinus. RESULTS In contrast to findings from other studies, the anti-Der p 1 level alone was not sufficient to disting…

AdultMaleAllergyNasal Provocation TestsAdolescentmedicine.medical_treatmentDermatophagoides pteronyssinusImmunologyProvocation testImmunoglobulin ENasal provocation testAirborne allergenSerologyYoung AdultmedicineImmunology and AllergyAnimalsHumansSerologic TestsAntigens DermatophagoidesSensitizationRetrospective StudiesSkin TestsHouse dust mitebiologybusiness.industryAllergensImmunoglobulin EMiddle Agedbiology.organism_classificationmedicine.diseaseRhinitis Allergicmedicine.anatomical_structureROC CurveImmunologybiology.proteinFemalebusinessJournal of investigational allergologyclinical immunology
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Modulation of Exposure to Static Magnetic Field Affects Targeted Therapy of Solid Tumors In Vivo

2018

Background Static magnetic fields (SMF) exhibit antitumoral activity and enhance the efficacy of chemotherapy by opening the tumor-blood barrier. This study aimed to analyze different SMF-exposure protocols on epidermal growth factor receptor (EGFR)-overexpressing tumors, as well as their combination with cetuximab. Materials and methods Experiments were performed in skinfold chamber preparations of C57Bl/6-and CD-1nu/nu mice bearing LLC-1 tumors. Animals were exposed to 587 mT magnetic field following different exposure protocols. A subgroup received additional cetuximab injections. Using in vivo-fluorescence microscopy and planimetry, tumor angiogenesis, growth and microcirculation were r…

MaleTumor angiogenesisCancer ResearchAngiogenesismedicine.medical_treatmentCetuximabMice Nude02 engineering and technology030218 nuclear medicine & medical imagingMicrocirculationTargeted therapyMice03 medical and health sciences0302 clinical medicineIn vivoNeoplasmsLeukocytesmedicineAnimalsEndotheliumEpidermal growth factor receptorCell ProliferationChemotherapyNeovascularization PathologicCetuximabbiologybusiness.industryMicrocirculationGeneral Medicine021001 nanoscience & nanotechnologyErbB ReceptorsMice Inbred C57BLMagnetic FieldsOncologyCancer researchbiology.protein0210 nano-technologybusinessmedicine.drugAnticancer Research
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