0000000000406777

AUTHOR

Heiko Tietgen

showing 2 related works from this author

ChemInform Abstract: Stereoselective Synthesis of 2-Substituted Pyrrolidines.

2000

Using O -pivaloyl protected D-galactopyranosylamine and D-arabinopyranosylamine, ( S ) or ( R ) configured α-substituted homoallylamines are synthesized with high diastereoselectivity by reaction of the corresponding aldimines with allyltributylstannane. Electrophile-induced endo -trig-cyclization of these N -glycosylhomoallylamines gave the 2-substituted pyrrolidines of high diastereomeric purity.

chemistry.chemical_classificationAldiminechemistryDiastereomerOrganic chemistryStereoselectivityGeneral MedicinePyrrole derivativesChemInform
researchProduct

Stereoselective Synthesis of 2-Substituted Pyrrolidines

2000

Using O-pivaloyl protected D-galactopyranosylamine and D-arabinopyranosylamine, (S) or (R) configured α-substituted homoallylamines are synthesized with high diastereoselectivity by reaction of the corresponding aldimines with allyltributylstannane. Electrophile-induced endo-trig-cyclization of these N-glycosylhomoallylamines gave the 2-substituted pyrrolidines of high diastereomeric purity.

chemistry.chemical_classificationAldimineNornicotinechemistry.chemical_compoundChemistryDiastereomerStereoselectivityGeneral ChemistryMedicinal chemistryCollection of Czechoslovak Chemical Communications
researchProduct