0000000000414047

AUTHOR

Peter Benz

showing 3 related works from this author

Radiation response non-invasively imaged by [18F]FDG-PET predicts local tumor control and survival in advanced oral squamous cell carcinoma

2003

It is a major challenge to preoperatively identify patients who will profit from surgery of advanced oral cancer. In multimodality therapy, response to neoadjuvant radiation correlates to treatment success. Hence, for preoperative decisions, assessment of treatment response is required. Therefore, we analysed the prognostic significance of glucose metabolism after preoperative radiotherapy. [(18)F]FDG-PET investigations were performed for re-staging 35 patients after neoadjuvant radiotherapy (36Gy) immediately prior to tumor resection. Emission and transmission measurements were obtained and SUV's were calculated for the sites of maximum [(18)F]FDG-uptake. Subpopulations of "low" (SUV4) and…

AdultMaleCancer Researchmedicine.medical_treatmentStandardized uptake valuePremisesFluorodeoxyglucose F18Odds RatiomedicineHumansRadical surgerySurvival rateSurvival analysisNeoadjuvant therapyAgedAged 80 and overAnalysis of Variancebusiness.industryMiddle AgedPrognosisNeoadjuvant TherapySurvival RateRadiation therapyTreatment OutcomeOncologyEpidermoid carcinomaMultivariate AnalysisCarcinoma Squamous CellFemaleMouth NeoplasmsRadiotherapy AdjuvantRadiopharmaceuticalsOral SurgeryNuclear medicinebusinessFollow-Up StudiesTomography Emission-ComputedOral Oncology
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Echogenicity of the substantia nigra in relatives of patients with sporadic Parkinson’s disease

2003

Increased echogenicity of the substantia nigra (SN) on ultrasound is a typical sonographic finding in Parkinson's disease (PD). Sonographic signal intensity of the SN is related to tissue iron content with higher iron level being associated with increased echogenicity. Recent findings indicate that hyperechogenicity of the SN represents an important susceptibility factor for nigrostriatal degeneration. In this study we determined the prevalence of a characteristic ultrasound sign of Parkinson's disease in first-degree relatives of PD patients. Fourteen patients with sporadic PD and 58 of their relatives underwent neurological, neuropsychological, and ultrasound examination. In addition, fou…

AdultMaleFluorine RadioisotopesPathologymedicine.medical_specialtyParkinson's diseaseUltrasonography Doppler TranscranialCognitive NeuroscienceSubstantia nigraNeuropsychological TestsHypokinesiamedicineHumansGenetic Predisposition to DiseaseGenetic TestingDominance CerebralProblem SolvingDominance (genetics)business.industryPutamenUltrasoundEchogenicityParkinson DiseaseMiddle Agedmedicine.diseaseDihydroxyphenylalanineTranscranial DopplerSubstantia NigraNeurologyNerve DegenerationFemalemedicine.symptomPsychologybusinessTomography Emission-ComputedNeuroImage
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Therapiemonitoring mittels 2-[18F]-FDG-Positronenemissionstomographie nach neoadjuvanter Strahlenbehandlung des Mundhöhlenkarzinoms

2001

Die Kombination strahlentherapeutischer und chirurgischer Behandlungsschritte beim Mundhohlenkarzinom erfordert eine fruhe, objektive Bewertung des Bestrahlungserfolgs. Schlechtes radiotherapeutisches Ansprechverhalten verlangt die moglichst umgehende chirurgische Sanierung auch bei hohem Operations- und Narkoserisiko. Eine deutliche Remission unter Strahlentherapie kann dagegen die Fortsetzung der Bestrahlungsbehandlung begrunden. Die vorliegende Studie untersucht daher die Bewertung des Bestrahlungserfolgs anhand der durch Positronenemissionstomographie (PET) bestimmten Glukosestoffwechselaktivitat.

Radiation therapyOncologyEpidermoid carcinomabusiness.industryNeoadjuvant treatmentmedicine.medical_treatmentmedicineRadiology Nuclear Medicine and imagingNuclear medicinebusinessOral cavityStrahlentherapie und Onkologie
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