0000000000414409

AUTHOR

Julia Suárez-gonzález

showing 4 related works from this author

Epidemiological, clinical and genomic snapshot of the first 100 B.1.1.7 SARS-CoV-2 cases in Madrid

2021

A new SARS-CoV-2 variant, B.1.1.7, emerged in September in the UK, and is responsible for 76.6% of COVID-19 cases.1 This variant has also been reported in another 45 countries, 17 of them European.2,3 B.1.1.7 is considered to have higher transmissibility.4 It carries an unusually high number of specific mutations/deletions, 18, mostly non-synonymous and eight concentrate in the S gene,5 including several which might have relevant functional roles. The 69/70 deletion may be associated to immune response evasion6 and the N501Y substitution increases the affinity to the ACE2 receptor.7 These findings have raised the alarm of having to face a new variant with the potential to accelerate the spr…

AdultMale2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)AdolescentSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)030231 tropical medicine03 medical and health sciencesYoung Adult0302 clinical medicineResearch LetterMedicineHumans030212 general & internal medicineUKChildB.1.1.7travelAgedAged 80 and overTravelbusiness.industrySARS-CoV-2InfantCOVID-19General MedicineGenomicsMiddle AgedSpainChild PreschoolFemalebusinessHumanitiesAcademicSubjects/MED00295
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Different Within-Host Viral Evolution Dynamics in Severely Immunosuppressed Cases with Persistent SARS-CoV-2

2021

12 páginas, 2 figuras, 1 tabla.

0301 basic medicineQH301-705.5medicine.medical_treatment030106 microbiologyInmunologíaMedicine (miscellaneous)GenomicsSingle-nucleotide polymorphismDiseaseBiologyArticleGeneral Biochemistry Genetics and Molecular BiologyVirusdiversityPersistence03 medical and health sciencesmedicinegenomicsBiology (General)Evolutionary dynamicsimmunosuppressedDiversitySARS-CoV-2COVID-19ImmunosuppressionGenomicspersistencemedicine.diseaseVirologyviral viabilityLymphoma030104 developmental biologyImmunosuppressedViral evolutionViral viability
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Overlapping of Independent SARS-CoV-2 Nosocomial Transmissions in a Complex Outbreak

2021

8 páginas, 2 figuras, 1 tabla.

AdultMalemedicine.medical_specialtyAdolescentCoronavirus disease 2019 (COVID-19)Health PersonnelSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Genome ViralMicrobiologyDisease OutbreaksYoung AdultNosocomial transmissionCase fatality rateEpidemiologyHealth careHumansMedicineMolecular BiologyPhylogenyAgedCross InfectionWhole Genome Sequencingbusiness.industryTransmission (medicine)SARS-CoV-2OutbreakCOVID-19Middle AgedGenomic epidemiologyHospitalsQR1-502HomogeneousEmergency medicineFemalebusinessResearch ArticlemSphere
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Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission

2021

9 páginas, 3 figuras. The data that support the findings of this study (Fastq files) are publicly available. Fastq files above the GISAID thresholds were deposited at GISAID (hCoV-19/Spain/MD-IBV-99007733/2020, hCoV-19/Spain/MD-IBV-99007151/2020, hCoV-19/Spain/MD-IBV-99007734/2020, and hCoV-19/Spain/MDIBV-99007170/2020). All sequences were also deposited at the ENA (European Nucleotide Archive; https:// www.ebi.ac.uk/ena/browser/home) (ERR5698024, ERR5697187, ERR6459974, ERR5698025, and ERR5697254).

Malemedicine.medical_specialtyPediatricsEpidemiologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PopulationContext (language use)MicrobiologySeverity of Illness IndexreinfectionEpidemiologyMedicineHumansTransmissionFamilySeroconversioneducationMolecular BiologyPhylogenyFirst episodeeducation.field_of_studyWhole Genome Sequencingbusiness.industryTransmission (medicine)SARS-CoV-2transmissionCOVID-19GenomicsMiddle AgedQR1-502SpainReinfectionFemaleContact TracingbusinessContact tracingResearch Article
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