Author: Coralie-anne Mosser

0000000000418282

AUTHOR

Coralie-anne Mosser

0000-0003-1485-8203

showing 1 related works from this author

Microglia in CNS development: Shaping the brain for the future

2017

Microglial cells are the resident macrophages of the central nervous system (CNS) and are mainly known for their roles in neuropathologies. However, major recent developments have revealed that these immune cells actively interact with neurons in physiological conditions and can modulate the fate and functions of synapses. Originating from myeloid precursors born in the yolk sac, microglial cells invade the CNS during early embryonic development. As a consequence they can potentially influence neuronal proliferation, migration and differentiation as well as the formation and maturation of neuronal networks, thereby contributing to the entire shaping of the CNS. We review here recent evidenc…

Central Nervous System0301 basic medicineMicrogliaGeneral NeuroscienceCentral nervous systemInflammationBiologymedicine.diseaseSynapse03 medical and health sciences030104 developmental biologyNeurodevelopmental disordermedicine.anatomical_structureImmune systemNeurodevelopmental DisordersmedicineAnimalsHumansMacrophage[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]MicrogliaNeuronmedicine.symptomNeuroscienceComputingMilieux_MISCELLANEOUS

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PEPhysical Sciences and Engineering
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SHSocial Sciences and Humanities
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