0000000000418702
AUTHOR
Pilar Moreno
Geographical and temporal structures of Legionella pneumophila sequence types in comunitat valenciana (Spain), 1998 to 2013
ABSTRACT Legionella pneumophila is an accidental human pathogen associated with aerosol formation in water-related sources. High recombination rates make Legionella populations genetically diverse, and nearly 2,000 different sequence types (STs) have been described to date for this environmental pathogen. The spatial distribution of STs is extremely heterogeneous, with some variants being present worldwide and others being detected at only a local scale. Similarly, some STs have been associated with disease outbreaks, such as ST578 or ST23. Spain is among the European countries with the highest incidences of reported legionellosis cases, and specifically, Comunitat Valenciana (CV) is the se…
Ultrasonic Echo Intensity as a New Noninvasive In Vivo Biomarker of Frailty
Objectives To investigate whether muscle quality based on echo intensity (EI) is associated with muscle strength (MS) and correlates with risk of frailty in elderly outpatients. Design Cross-sectional, experimental study. Setting Outpatient clinic. Participants Individuals aged 20 to 90 (N = 112). Individuals aged 20 to 59 participated as controls. Those aged 60 and older participated in the experimental group and were subdivided into robust, prefrail, and frail according to the Fried frailty criteria. Measurements EI, muscle thickness (MT), and subcutaneous fat thickness (SFT) of the anterior compartment of the thigh were measured using ultrasound images. MS was quantified using a hand dyn…
Utilidad de la administración de topiramato en pacientes con agresividad y consumidores de drogas, asociada o no a psicoterapia
Objetivo: Analizar la evolución de la agresividad-ira y de los consumos en pacientes agresivos, dependiendo de la intervención realizada (topiramato vs. psicoterapia).Material y método: Estudio retrospectivo multicéntrico realizado sobre una muestra de 49 pacientes con problemas de ira y/o agresividad. Se revisaron sus historias, evaluando los datos iniciales y a los 6 meses de puntuación en escala STAXI, consumos, e impresión clínica global. Estos datos se relacionaron con el tipo de tratamiento recibido: tratamiento farmacológico con topiramato, psicoterapia, ambas, o ninguna de las anteriores.Resultados: Estado de ira STAXI: La mejor opción es la psicoterapia, tanto sola (37%) como asoci…