EFFECTS OF TMS OVER RIGHT POSTERIOR PARIETAL CORTEX AND VISUOSPATIAL NEGLECT IN NEAR AND FAR SPACE USING LINE BISECTION

Are paradoxical intensity-dependent effects of 5Hz rTMS train in motor cortex of migraine with aura patients evidence of abnormal homeostatic plasticity

SHORT-TERM SYNAPTIC PLASTICITY IN MIGRAINE MOTOR CORTEX: EVIDENCE BY PRECONDITIONING OF HIGH-FREQUENCY REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (rTMS) WITH TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS).

Background: Brief 5Hz repetitive transcranial magnetic stimulation (rTMS) trains at 120% of the resting- motorthreshold (RMT) intensity determine in healthy subjects a potentiation of motor evoked potentials (MEPs), likely due to short-term presynaptic plasticity facilitation. We recently showed paradoxical intensity-dependent MEP changes to 5Hz rTMS in migraine with MEP facilitation at 110% and inhibition at 130% RMT. This provides evidence of both hyper-responsivity and self-limiting hyperexcitability capacity in migraine, likely due to earlier activation of inhibitory homeostatic plasticity mechanisms. To explore this, we applied in migraineurs cathodal transcranial Direct Current Stimul…

Allodinia, Disabilità E Parametri Clinici Dell’emicrania: Risultati Di Uno Studio Con Questionario Retrospettivo In Pazienti Affetti Da Emicrania