0000000000424404

AUTHOR

Pedro Idigoras

showing 3 related works from this author

Neisseria gonorrhoeae antimicrobial resistance in Spain: a prospective multicentre study.

2021

Abstract Objectives Gonococcal infection is one of the most reported sexually transmitted infections and antimicrobial resistance in Neisseria gonorrhoeae (NG) is challenging for the treatment of this infection. This observational study aimed to describe antimicrobial resistance of NG and epidemiological data from patients with gonococcal infection in eight regions of Spain, for updating the local therapeutic guidelines. Methods MICs of penicillin, cefixime, ceftriaxone, azithromycin, ciprofloxacin, fosfomycin and gentamicin were determined by Etest for all NG isolates recovered from 1 April 2018 to 30 September 2019 from 10 hospitals in Spain. Resistance determinants were identified using …

0301 basic medicineMicrobiology (medical)Malemedicine.medical_specialty030106 microbiologyMicrobial Sensitivity TestsFosfomycinAzithromycinAzithromycinmedicine.disease_cause03 medical and health sciencesGonorrheaSexual and Gender Minorities0302 clinical medicineAntibiotic resistanceCiprofloxacinInternal medicineDrug Resistance BacterialmedicineHumansPharmacology (medical)030212 general & internal medicineProspective StudiesHomosexuality MaleEtestPharmacologybusiness.industryCeftriaxoneNeisseria gonorrhoeaeAnti-Bacterial AgentsPenicillinCiprofloxacinInfectious DiseasesSpainNeisseria gonorrhoeaebusinessCefiximemedicine.drugThe Journal of antimicrobial chemotherapy
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Molecular evolution and complete genome sequences in forensic analysis: Neisseria gonorrhoeae in a transmission case

2019

Molecular epidemiology and phylogenetic analyses are frequently used in the investigation of viral transmission cases in forensic contexts. Here, we present the methods and results of the analysis of a bacterial transmission in an alleged child abuse case using complete genome sequences obtained by high-throughput sequencing (HTS) methods.

Child abuseHigh-throughput sequencingMolecular epidemiologyPhylogenetic treeComputational biologyBiologymedicine.disease_causeGenomeDNA sequencingPathology and Forensic Medicinelaw.inventionTransmission (mechanics)lawMolecular evolutionBayes factorsGeneticsNeisseria gonorrhoeaemedicinephylogenetic treeMaximum likelihoodPhylogenetic tree
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Whole-genome sequencing of Neisseria gonorrhoeae in a forensic transmission case.

2019

Abstract Molecular epidemiology and phylogenetic analyses are frequently used in the investigation of viral transmission cases in forensic contexts. Here, we present the methods and results of the analysis of a bacterial transmission episode in an alleged child abuse case using complete genome sequences obtained by high-throughput sequencing (HTS) methods. We obtained genomes of Neisseria gonorrhoeae from the victim, the suspect, and 29 unrelated controls. The analysis of the genomes revealed that the victim and suspect isolates had identical sequences in both the bacterial chromosome and the single plasmid present in them. One of the local controls was very similar (differing in only 2 SNP…

0301 basic medicineChild abuseMaleBacterial genome sizeBiologyGenomePolymerase Chain ReactionPolymorphism Single NucleotideDNA sequencingPathology and Forensic Medicine03 medical and health sciencesGonorrhea0302 clinical medicineGeneticsHumans030216 legal & forensic medicineTypingChildGeneticsWhole genome sequencingLikelihood FunctionsMolecular epidemiologyWhole Genome SequencingHigh-Throughput Nucleotide SequencingChild Abuse SexualSequence Analysis DNANeisseria gonorrhoeaeElectrophoresis Gel Pulsed-Field030104 developmental biologyVaginaMultilocus sequence typingFemaleMultilocus Sequence TypingForensic science international. Genetics
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