0000000000424592

AUTHOR

Emmanuelle Nedelec

showing 3 related works from this author

Glucose homeostasis is impaired in mice deficient for the neuropeptide 26RFa (QRFP)

2019

AbstractIntroduction26RFa (QRFP) is a biologically active peptide that has been found to control feeding behaviour by stimulating food intake, and to regulate glucose homeostasis by acting as an incretin. The aim of the present study was thus to investigate the impact of 26RFa gene knockout on the regulation of energy and glucose metabolism.Research design and methods26RFa mutant mice were generated by homologous recombination, in which the entire coding region of prepro-26RFa was replaced by the iCre sequence. Energy and glucose metabolism was evaluated through measurement of complementary parameters. Morphological and physiological alterations of the pancreatic islets were also investigat…

medicine.medical_specialtyPancreatic isletsInsulinmedicine.medical_treatmentQRFPIncretinCarbohydrate metabolismBiologymedicine.diseaseEndocrinologymedicine.anatomical_structureDiabetes mellitusInternal medicinemedicineGlucose homeostasisPancreas
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Crosstalk between hypothalamic neurons and olfactory system: a tracing and anatomo-fuctional investigation in mouse

2014

[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutrition[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Evaluation of the 26RFa/GPR103 peptidergic system in a mouse model of insulinopenia

2021

International audience

[SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism[SDV] Life Sciences [q-bio][SDV]Life Sciences [q-bio][SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC][SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC][SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismComputingMilieux_MISCELLANEOUS
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