0000000000425273

AUTHOR

Marcello Disertori

showing 3 related works from this author

Deterioration of organization in the first minutes of atrial fibrillation: A beat-to-beat analysis of cycle length and wave similarity

2007

Deterioration of AF Organization. Introduction: It has been recently suggested that many episodes of atrial fibrillation (AF) may be partially organized at the onset and thus more suitable for antitachycardia pacing therapy. Nevertheless, the time course of organization in the first minutes of AF has not been quantified yet. Methods and Results: Twenty episodes of paroxysmal AF were studied. Electrograms were recorded from the right atrium (RA), distal (CSd), and proximal coronary sinus (CSp). The time course of AF cycle length (AFCL) and the regularity of wave morphology (similarity index S) were beat-to-beat measured at each recording site during the first 7 minutes of AF. AFCL and S show…

Malemedicine.medical_specialtyPhysiologyBeat (acoustics)Severity of Illness IndexHeart Conduction SystemHeart RateAF organizationPhysiology (medical)Internal medicineHeart ratemedicineHumansElectrogram analysiCycle lengthCoronary sinusFibrillationbusiness.industryAntitachycardia pacingAtrial fibrillationMiddle AgedPrognosismedicine.diseaseAtrial fibrillationAF time courseSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaAntitachycardia PacingCardiologyFemalemedicine.symptomElectrical conduction system of the heartElectrophysiologic Techniques CardiacbusinessCardiology and Cardiovascular MedicineFollow-Up Studies
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Causal linear parametric model for baroreflex gain assessment in patients with recent myocardial infarction

2001

Spectral and cross-spectral analysis of R-R interval and systolic arterial pressure (SAP) spontaneous fluctuations have been proposed for noninvasive evaluation of baroreflex sensitivity (BRS). However, results are not in good agreement with clinical measurements. In this study, a bivariate parametric autoregressive model with exogenous input (ARXAR model), able to divide the R-R variability into SAP-related and -unrelated parts, was used to quantify the gain (αARXAR) of the baroreflex regulatory mechanism. For performance assessing, two traditional noninvasive methods based on frequency domain analysis [spectral, baroreflex gain by autogressive model (αAR); cross-spectral, baroreflex gain…

medicine.medical_specialtyPhysiologySystoleEntropyRR intervalMyocardial InfarctionHemodynamicsBlood PressureBaroreflexAutoregressive modelSpectral analysiElectrocardiographyPhenylephrineHeart RateInternal medicinePhysiology (medical)MedicineHumansVasoconstrictor AgentsIn patientAnalysis of VarianceModels Statisticalbusiness.industryModels CardiovascularBaroreflexMiddle AgedR-R-SAP transfer functionSurgeryBlood pressureBaroreflex sensitivityParametric modelCardiologySystolic arterial pressureRegression AnalysisCardiology and Cardiovascular MedicinebusinessRecent myocardial infarction
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Evidence of unbalanced regulatory mechanism of heart rate and systolic pressure after acute myocardial infarction

2002

The interactions between systolic arterial pressure (SAP) and R-R interval (RR) fluctuations after acute myocardial infarction (AMI) were investigated by measures of synchronization separating the feedback from the feedforward control and capturing both linear and nonlinear contributions. The causal synchronization, evaluating the ability of RR to predict SAP (χs/t) or vice versa (χt/s), and the global synchronization (χ) were estimated at rest and after head-up tilt in 35 post-AMI patients, 20 young and 12 old. Significance and nonlinearity of the coupling were assessed by surrogate data analysis. Tilting increased the number of young subjects in which RR-SAP link was significant (from 17…

Adultmedicine.medical_specialtyPhysiologyMyocardial InfarctionHemodynamicsBlood PressureSynchronizationAutonomic Nervous SystemHeart RatePhysiology (medical)Internal medicineHeart ratemedicineNonlinear couplingHumansMyocardial infarctionNonlinear couplingAgedFeedback PhysiologicalSurrogate data analysisbusiness.industryCausal analysicausal analysis; nonlinear coupling; synchronization; baroreflex regulationcausal analysisBaroreflexMiddle Agedmedicine.diseaseEndocrinologyBlood pressureNeural regulationSystolic arterial pressureCardiologyBaroreflex regulationCardiology and Cardiovascular Medicinebusiness
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