0000000000427619

AUTHOR

Robert W. Owen

showing 2 related works from this author

Diagnosis of lung cancer by canine olfactory detection in urine and breath samples.

2019

e13067 Background: Lung cancer is the leading oncological cause of death in western countries. The WHO estimated 2.09 million newly diagnosed lung cancer patients in 2018 worldwide. Although early detection is crucial for patients outcome, no surveillance tools exist. Dogs have a highly sensitive olfactory system which is already used in several ways, such as drug and ketone detection. The aim of the study was to evaluate the capability of a classically conditioned domestic dog to accurately distinguish samples of lung cancer patients of all tumor stages in urine and breath from healthy controls. Methods: This monocentric clinical trial was an original study and approved by the local ethic…

Cancer Researchmedicine.medical_specialtybusiness.industryNewly diagnosedUrinemedicine.diseaseGastroenterology03 medical and health sciences0302 clinical medicineOncology030220 oncology & carcinogenesisInternal medicinemedicineLung cancerbusiness030215 immunologyCause of deathJournal of Clinical Oncology
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Pesticide analysis in coffee leaves using a quick, easy, cheap, effective, rugged and safe approach and liquid chromatography tandem mass spectrometr…

2017

An analytical method using a quick, easy, cheap, effective, rugged and safe (QuEChERS) procedure for multi-residue determination of 52 pesticides in coffee leaf extractshas been developed and validated according to SANTE/11945/2015 guidelines. Different sorbent combinations for dispersive solid phase extraction (d-SPE) clean-up as well as dispersive liquid-liquid microextraction (DLLME) were tested. The relative standard deviations (RSDs) for the recovery of 87-94% of pesticides added to coffee leaf extracts,was ≤20% for samples spiked at concentrations up to 50ng*g-1 depending on the clean-up procedures. However, samples spiked with a 100ng*g-1 pesticide mixture gave RSDs>20% for most pest…

SorbentCoffeaFood Contamination010402 general chemistryQuechers01 natural sciencesBiochemistryCoffeeAnalytical ChemistryLiquid chromatography–mass spectrometryTandem Mass SpectrometrySolid phase extractionChromatographyChemistry010401 analytical chemistryOrganic ChemistryExtraction (chemistry)Solid Phase ExtractionPesticide ResiduesGeneral MedicineOrganic coffeePesticide0104 chemical sciencesClean-upPlant LeavesAdsorptionChromatography LiquidJournal of chromatography. A
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