0000000000427668

AUTHOR

Marina Bianchi

showing 3 related works from this author

Derivatives of Erythropoietin That Are Tissue Protective But Not Erythropoietic

2004

Erythropoietin (EPO) is both hematopoietic and tissue protective, putatively through interaction with different receptors. We generated receptor subtype–selective ligands allowing the separation of EPO's bioactivities at the cellular level and in animals. Carbamylated EPO (CEPO) or certain EPO mutants did not bind to the classical EPO receptor (EPOR) and did not show any hematopoietic activity in human cell signaling assays or upon chronic dosing in different animal species. Nevertheless, CEPO and various nonhematopoietic mutants were cytoprotective in vitro and conferred neuroprotection against stroke, spinal cord compression, diabetic neuropathy, and experimental autoimmune encephalomyeli…

Encephalomyelitis Autoimmune ExperimentalEncephalomyelitiscarbamylated erythropoietinApoptosisPharmacologyLigandsNeuroprotectionRats Sprague-DawleyMiceStructure-Activity RelationshipDiabetic Neuropathiesddc:570hemic and lymphatic diseasesReceptors ErythropoietinmedicineAnimalsHumansErythropoiesisReceptorErythropoietinCells CulturedNeuronsMice Inbred C3HBinding SitesMultidisciplinaryChemistryExperimental autoimmune encephalomyelitisErythropoietin; erythropoietin receptor; carbamylated erythropoietin; neuroprotective agentsmedicine.diseaseRecombinant ProteinsRatsErythropoietin receptorStrokeNeuroprotective AgentsErythropoietin Erythropoietin derivative NeuroprotectionHematocritMutagenesisErythropoietinDrug DesignImmunologyErythropoiesisFemaleNervous System DiseasesSignal transductionerythropoietin receptorSpinal Cord CompressionSignal Transductionmedicine.drugScience
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Aspirin After Oral Anticoagulants for Prevention of Recurrence in Patients with Unprovoked Venous Thromboembolism. the Warfasa STUDY

2011

Abstract Abstract 543 Background A recurrence occurs in 15–20% of patients with unprovoked venous thromboembolism (VTE) in the two years after the withdrawal of oral anticoagulant treatment. Extending anticoagulant treatment is effective but associated with increased bleeding risk. We assessed the efficacy and safety of aspirin for the prevention of VTE recurrence after a conventional course of oral anticoagulation. Methods Warfasa was an investigator-initiated double-blind randomized placebo-controlled event-driven study. Patients with a first-ever unprovoked VTE who had completed 6–12 months of oral anticoagulant treatment were randomized to receive aspirin, 100 mg daily, or placebo for a…

medicine.medical_specialtyAspirinbusiness.industryIncidence (epidemiology)ImmunologyHazard ratioCell BiologyHematologyPlaceboRelapse preventionBiochemistrySurgeryInternal medicinemedicineIn patientbusinessVenous thromboembolismOral anticoagulationmedicine.drugBlood
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La heterodoxia en la poesía visual española del siglo XXI

2014

Resumen: Toda vanguardia esconde un malestar y una rebeldia contra la realidad que aflige al individuo y que se vuelve objeto de critica en las obras. En este sentido, tras aclarar a que nos referimos cuando hablamos de poesia visual, analizaremos algunas obras que han aparecido por primera vez en 2014, interpretandolas como reaccion contra la perdida de valores de la sociedad postmoderna. La finalidad sera demostrar que la poesia visual espanola del siglo XXI no ha renunciado a su heterodoxia, puesto que elige justamente este universo donde todo es rapido, fluido, superficial, complejo e inasible para seguir denunciando desde su interior la incomunicacion y la alienacion a la que nos han l…

Cultural StudiesLinguistics and LanguageHistoryLiterature and Literary Theorycultura de masasVisual poetryVisual poetryAlienationPoesía visualpoesíaLanguage and Linguisticsethical commitmentpoesía visual compromiso ético cultura de masas incomunicación alienaciónmass culturealienaciónMass culturepoesía española conteporáneaCommunicationPhilosophycompromiso éticoVisual poetry; ethical commitment; mass culture; incommunication; alienation;incommunicationSettore L-LIN/05 - Letteratura SpagnolaPoesía visual; compromiso ético; cultura de masas; incomunicación; alienación;alienationLiteraturaLiteratura; poesíaHumanitiesEthical commitmentincomunicaciónKamchatka. Revista de análisis cultural.
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