0000000000429836

AUTHOR

Hausamen Je

showing 2 related works from this author

Preoperative radiochemotherapy and radical surgery in comparison with radical surgery alone. A prospective, multicentric, randomized DÖSAK study of a…

1994

Abstract A multicentric, randomized study of squamous cell carcinoma (SCC) of the oral cavity and the oropharynx has been undertaken by DOSAK. The results after radical surgery alone have been compared with the results of combined preoperative radiochemotherapy followed by radical surgery. Patients with primary (biopsy proven) SCC of the oral cavity or the oropharynx with tumor nodes metastasis (TNM) stages T2–4, N0–3, M0 were included in the study. A total of 141 patients were treated by radical surgery alone, whereas 127 patients were treated by radical surgery preceded by preoperative radiochemotherapy. The preoperative treatment consisted of conventionally fractioned irradiation on the …

Malemedicine.medical_specialtymedicine.medical_treatmentlaw.inventionMetastasisRandomized controlled triallawPreoperative CareBiopsymedicineHumansLife TablesProspective StudiesRadical surgerySurvival analysisChemotherapymedicine.diagnostic_testbusiness.industryMiddle Agedmedicine.diseaseCombined Modality TherapySurgerySurvival RateRadiation therapyLog-rank testOropharyngeal NeoplasmsOtorhinolaryngologyLymphatic MetastasisCarcinoma Squamous CellFemaleMouth NeoplasmsSurgeryCisplatinNeoplasm Recurrence LocalOral SurgerybusinessFollow-Up StudiesInternational Journal of Oral and Maxillofacial Surgery
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Preoperative Radiochemotherapy and Radical Surgery of Advanced Head and Neck Cancers — Results of a Prospective, Multicenter DÖSAK Study

1994

Present research concerning the efficiacy of therapeutic strategies for squamous cell carcinomas of the oral cavity and the oropharynx profits from former observational studies. The so-called retrospective German, Austrian, and Swiss Association for Head and Neck Tumors (DOSAK) study (Platz et al. 1986) served to review existing proposals for classification (UICC 1973, 1978; AJC 1978) and to develop a statistical classification which enables the head and neck oncologist to define prognostically homogeneous patient collectives. The treatment-dependent prognostic index (TPI) was the corresponding result (Platz et al. 1982).

Oncologymedicine.medical_specialtybusiness.industryMultimodality TreatmentHead and neck tumorsOral cavityHomogeneousInternal medicinemedicineObservational studyRadical surgeryTumor node metastasisbusinessHead and neck
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