0000000000434535

AUTHOR

Manuela Piccinnu

showing 2 related works from this author

Surveillance as determinant of long-term survival in non-transplanted hepatocellular carcinoma patients

2021

Purpose: We aimed at assessing the impact of surveillance on long-term survival in HCC patients. Methods: From the ITA.LI.CA database, we selected 1028 cases with long (≥5 years, LS group) and 2721 controls with short-term survival (&lt

Cancer Researchmedicine.medical_specialtyHepatocellular carcinomaSettore MED/12 - GASTROENTEROLOGIACancer stageIndependent predictorLogistic regressionlcsh:RC254-282Article03 medical and health sciencesLong-term survival0302 clinical medicineInternal medicineLong term survivalmedicineTreatment.Surveillancebusiness.industryCancer stageSettore MED/09 - MEDICINA INTERNAConfoundingmedicine.diseaselcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensTreatmentCancer stage; Hepatocellular carcinoma; Long-term survival; Surveillance; TreatmentOncology030220 oncology & carcinogenesisHepatocellular carcinomaBaseline characteristics030211 gastroenterology & hepatologybusiness
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Surveillance for hepatocellular carcinoma with a 3-months interval in “extremely high-risk” patients does not further improve survival

2022

Abstract Background An enhanced surveillance schedule has been proposed for cirrhotics with viral etiology, who are considered at extremely high-risk of hepatocellular carcinoma (HCC). Aims We compared the 3- and 6-months surveillance interval, evaluating cancer stage at diagnosis and patient survival. Methods Data of 777 HBV and HCV cirrhotic patients with HCC diagnosed under a 3-months (n = 109, 3MS group) or a 6-months (n = 668, 6MS group) surveillance were retrieved from the Italian Liver Cancer database. Survival in the 3MS group was considered as observed and adjusted for lead-time bias, and survival analysis was repeated after a propensity score matching. Results The 3-months surveil…

medicine.medical_specialtyCarcinoma HepatocellularSurvivalHepatocellular carcinomaCancer stageCancer stage; Hepatocellular carcinoma; Surveillance interval; SurvivalInternal medicinemedicineHumansPropensity ScoreSurveillance intervalSurvival analysisHigh risk patientsHepatologybusiness.industryCancer stageLiver NeoplasmsSettore MED/09 - MEDICINA INTERNAGastroenterologyPatient survivalmedicine.diseaseSurvival AnalysisHepatocellular carcinomaPropensity score matchingSurvival AnalysiLiver cancerbusinessMedian survivalHuman
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