0000000000443383
AUTHOR
G. Campisi
showing 53 related works from this author
Is resective surgery still the best practice for ONJ stage III? A case report of a conservative therapy
2017
DOCTORAL: THE FREE APP FOR TUTORING IN SUPPORTIVE ORAL CARE
2018
To introduce the version 2.0 of DoctOral free app, created for tutoring medical/dental professionals (and students) in the clinical recognition of oral lesions and dental treatment planning in patients at risk of ONJ drug- related.
Ozone gas insufflation and infiltration for conservative surgical treatment of osteonecrosis of the jaw: preliminary results at 3 months
2018
the aim of this study was to evaluate efficacy and safety of ozone insufflation/injection in conservative surgical approaches of oNJ in two cancer patients.
GOTeC: INTERDISCIPLINARY TUMOR BOARD FOR THE DIAGNOSIS AND TREATMENTS OF HEAD AND NECK CANCERS
2018
Survivin detection in saliva samples from patients with oral squamous cell carcinoma
2007
L’odontoiatria a misura del paziente con patologia osteometabolica a rischio di osteonecrosi delle ossa mascellari da farmaci.
2016
L’osteonecrosi delle ossa mascellari (ONJ) da farmaci è una severa patologia odontoiatrica, recentemente defi nita come «una reazione avversa farmacocorrelata, caratterizzata dalla progressiva distruzione e necrosi dell’osso mandibolare e/o mascellare di soggetti esposti al trattamento con farmaci per cui sia accertato un aumentato rischio di malattia, in assenza di un pregresso trattamento radiante»1-3. I pazienti osteometabolici a rischio di sviluppare l’ONJ sono quelli sottoposti a terapia con bisfosfonati (in particolare aminobisfosfonati o Nitrogen-containing BisPhosphonate/NBP) e, più recentemente, con denosumab (anticorpo monoclonale anti-RANKL)4. Tali farmaci antiriassorbitivi carat…
lynphoepithelial carcinoma in a HCv patient: a case report
2018
Oral Lichen Planus: a new experimental therapeutic protocol by means of oxygen-ozone mixture injection.
2019
Comments on "diagnosis and management of osteonecrosis of the jaw: A systematic review and international consensus"
2015
Letter to editor
High quality extra virgin olive oil from olives attacked by the olive fruit fly, Bactrocera oleae (Rossi) (Diptera Tephritidae): which is the tolerab…
2017
The infestation due to the olive fruit fly, Bactrocera oleae (Rossi), the key pest in most of world olive groves, has been monitored in six years, from 2004 to 2008 and in 2014, in eight coastal Sicilian olive groves consisting of ‘Cerasuola’ and ‘Nocellara del Belice’ cultivars. Infestation was recorded following the classical sampling method based on olive collection and dissection, in order to count live olive fruit fly instars (eggs, larvae and pupae) and exit holes. Four different infestation indexes, all of them calculated using data recorded at harvest, have been used to assess their relationship with the main three quality parameters of the olive oil obtained from the same olive sam…
POSSIBLE ROLE OF CRY1 AND CRY2 IN ORAL CARCINOGENESIS
2014
Aim. Dysfunction of the circadian clock is involved in tumorigenesis, and altered expression of some clock genes has been found in cancer patients. It has been shown recently that the occurrence, development, prognosis, and treatment of cancer are closely related to the abnormal expression of certain circadian-clock genes. CRY1 and CRY2 circadian-clock gene plays an important role in the regulation of many normal hysiological rhythms. This proteins act as light-independent inhibitors of CLOCK-BMAL1 components of the circadian clock. It has been revealed recently that abnormal expression of CRY1 and CRY2 correlate closely with the occurrence and development of many cancers. However, the expr…
REVERSE ELECTRODIALYSIS FOR POWER PRODUCTION FROM OILFIELD WASTEWATERS
2022
Produced waters (PWs) are wastewaters generated by crude-oil extraction processes. They can present very different characteristics depending on the field location and production process. Dispersed oil, dissolved organics and solid particles are usually the main components. Moreover, PWs can contain a very high quantity of dissolved salts 1, with a total dissolved solid (TDS) concentration up to 300 g/L. Each barrel of extracted oil requires the simultaneous extraction of 3 barrels of produced water2 on average. PWs are often discharged into the sea, or sent in evaporation ponds thus leading to a dramatic environment impact3. Reinjection in the extraction well is currently the most common an…
Differential diagnosis of diffused oral mucosal pigmented lesion: a case of Dubreuilh’s melanosis
2019
OSTEONECROSIS OF THE JAW RELATED TO NON- ANTIRESORPTIVE MEDICATIONS/THERAPIES: A SYSTEMATIC REVIEW
2018
To review characteristics of ONJ in cancer patients receiving non- antiresorptive medications.
A misleading infection in a psoriatic patient: a challenging diagnosis of orocutaneous leishmaniasis
2019
Oral squamous cell carcinoma as a complication of chronic graft-versus-host disease: a case report
2014
Objectives. Chronic Graft-Versus-Host Disease (cGVHD) is an immunoregulatory disorder which occurs after allogeneic hematopoietic-cell transplantation (HCT) and often shares features of autoimmunity and immunodeficiency. GVHD related oral manifestations include severe oral pain, xerostemia, ulcerative lesions, and mucositis. Furthermore,a major late suggested complication of HSCT is the dramatically increased risk of secondary malignancies including oral cancer and oral cGVHD-releted inflammation may be considered a potential risk factor. Case report. A 51-year-old male patient referred in 1994 to our surgery for cGVHD oral lesions secondary to HCT for acute myelogenous leukemia developed i…
Transbuccal tablets of carbamazepine: formulation, release and absorption pattern.
2006
Tranbsuccal drug administration is an attractive method, as it has several advantages especially with respect to peroral delivery. Here we report: i) the aptitude of carbamazepine (CBZ) to penetrate porcine buccal mucosa and reconstituted human oral (RHO) epithelium; ii) three different tablet formulations for transbuccal administration; iii) the drug release rate from tablets. CBZ permeation through the buccal mucosa was investigated by using two different bi-compartmental open models: Franz cells for porcine buccal mucosa and Transwell diffusion cells system for RHO epithelium. Results, expressed as drug flux (Js) and permeability coefficients (Kp), indicated that CBZ well penetrates the …
Optical Coherence Tomography (OCT) and Oral Potentially Malignant Disorders: critical review on potential diagnostic patterns
2022
Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study
2017
Objectives: Osteonecrosis of the jaw (ONJ) is a potentially severe adverse effect of bisphosphonates (BP). Although the risk of ONJ increases with increasing duration of BP treatment, there are currently no reliable estimates of the ONJ time to onset (TTO). The objective of this study was to estimate the TTO and associated risk factors in BP-treated patients. Subjects and Methods: Retrospective analysis of data from 22 secondary care centres in seven countries relevant to 349 patients who developed BP-related ONJ between 2004 and 2012. Results: The median (95%CI) TTO was 6.0 years in patients treated with alendronate (n = 88) and 2.2 years in those treated with zoledronate (n = 218). Multiv…
knowledge, practice and attitude about OSCC prevention among Calabrian primary care physicians: an observational study
2018
3D OSCC model: effects following topical 5-FU delivery by drug-loaded tablets
2012
Current status in buccal drug delivery
2008
This article overviews the progress made in buccal drug delivery research during the last five years and reports a new high-tech approach to achieve controlled delivery.
pD-l1 expression in oral squamous cell carcinoma microenvironment and prognostic correlations
2018
Backgroun of this study is to investigate the PD-l1 expression in the Microenvironment of oral Squamous cell carcinoma (oScc) samples and its correlation to prognostic data.
Principal adverse events due to everolimus therapy. A systematic review of the literature
2019
Fuzzy neural networks to evacuate expression of cell cycle markers in OSCC HPV-positive.
2005
Ozone insufflation and l-prf application in an idiopathic and recurrent case of osteonecrosis of the maxilla
2019
Surgical treatment of medication-related osteonecrosis of the jaws with addiction of L-PRF: preliminary results
2018
Osteonecrosis of the jaw related to everolimus and bisphosphonate: a unique case report?
2013
Osteonecrosis of the jaw (ONJ) is a rare but serious lesion of the jaw, characterized mainly by exposed necrotic bone;it is related to various drugs, usually used for treating patients with advanced malignancies. Drugs implicated in ONJ are: nitrogen-containing bisphosphonates (NBPs), denosumab, anti-angiogenic drugs (e.g bevacizumab, sunitinib,sorafenib) and the selective mammalian target of rapamycin mTOR, everolimus. Previous data regarding the combining of NBPs with antiangiogenic agents conflict with some reports (indicating a similar risk of ONJ compared with the use of NBPs alone1); other reports show significantly higher rates (18% vs 1% with NBPs alone) of the incidence of ONJ2. Th…
Early detection of amyloid light-chain amyloidosis: a case report of oral primary manifestation
2018
Oral pathology in untreated coeliac disease
2007
Oral health assessment in palliate patients: an exploratory preliminary survey
2017
Extrahepatic spread of hepatocellular carcinoma
2012
Hepatocellular carcinoma (HCC) is a major health problem. The treatment of HCC depends on the tumour stage and on the severity of underlying cirrhosis, however, a majority of HCC patients have advanced disease at presentation. In recent years extra-hepatic spread (ES) of HCC seems to have been observed more frequently than in the past even if few data exist in literature on prevalence, clinical presentation and prognosis of patients with HCC ES. Aim of this brief review is underline the main concerns, pitfalls and warnings in practicing with these patients. ES of HCC are not rare, and the probability of finding ES is higher in patients with advanced intra-hepatic HCC. The more frequent ES s…
Malignant transformation of oral leukoplakia in oral squamous cell carcinoma: a case report.
2022
Pain management in osteonecrosis of jaw (ONJ): an orphan issue?
2018
We performed a systematic review of oNJ literature with keyword and MeSH terms referred to pain and its treatment, on PubMed and other literature sources on 2014-2018 years. out of 2957 publications citing oNJ and published in the period, 350 papers reported about pain anyhow.
New perspectives in medical approach to therapy of head and neck squamous cell carcinoma
2009
Head and neck cancer is the eighth most common cause of cancer death worldwide. Its incidence varies widely among different regions. In North America and the European Union, head and neck cancer accounts for 3% to 4% of all cancer diagnoses. Conversely, in Southeast Asia and Africa, head and neck cancer accounts for approximately 8% to 10% of all cancers1. Although the incidence of head and neck cancers has decreased slightly from 1975 to 2002 in the United States5, approximately 46 000 new cases are still expected in 2007 alone. Even if surgery and radiotherapy have remained the core therapy in squamous cell carcinoma of the head and neck (HNSCC). Radiotherapy following surgery was the sta…
Bisphosphonate related osteonecrosis of the jaws in Italy: an observational report of 24 cases
2018
Development of OloHealth, a teledentistry platform for the ONJ prevention in Sicily: preliminary reports
2018
New horizons for OSCC chemotherapy: transmucosal permeability of 5-fluorouracil throughout porcine buccal mucosa
2007
Interventions for treating osteonecrosis of the jaw stage III: may conservative surgical management be a viable option?
2018
Gingivitis
2017
Gingival inflammation is caused by bacterial plaque (dental biofilm) that accumulates daily on the teeth.Results in redness, slight swelling, or "puffiness" of the gums and bleeding on tooth brushing. Treatment involves thorough professional tooth cleaning and effective daily removal of dental plaque by tooth brushing and cleaning between the teeth. Necrotising ulcerative gingivitis (NUG) is a more serious condition that is mainly found in developing countries associated with people with severe malnutrition or HIV/AIDS with low CD4 T-cell counts.
Epithelial-myoepithelial carcinoma of the minor salivary glands: a case report
2018
Concept therapy: Interdisciplinary tumor board for the diagnosis and treatments of head and neck cancer
2017
Prevalence of vulval lichen planus in a cohort of women with oral lichen planus:an interdisciplinary study
2006
BACKGROUND: Lichen planus (LP) is a mucocutaneous inflammatory dermatosis that frequently involves the oral and genital mucosae. Patients with LP affecting these sites are often seen by oral medicine specialists or gynaecologists who work in isolation and depend heavily on histopathologists to help them in confirming the diagnosis. There are few studies in the literature combining the experiences of these specialists who share the care of patients with both oral and genital LP. OBJECTIVES: To estimate the prevalence of vulval LP (VLP) in a cohort of patients with histologically confirmed oral LP (OLP). METHODS: The study group consisted of 42 women histologically diagnosed with OLP. The mea…
A strange “butterly-like” ulcer of the palate. May be it the results of an underlying trombotic event in a predisposed patient?
2013
Occurrence of oro-facial malformations in a tertiary center hospital of Southern Italy: retrospective study on ten thousand newborns
2015
Congenital anomalies (CA) are one of the major cause of infant mortality and childhood morbitity, affecting 2-3% of all babies. Approximately 1% of these newborns have syndromes or multiple anomalies; Cranio-facial anomalies are often a component part of these pathologies. Several newborns with cranio-facial anomalies are affected by syndromes composed of multiple malformations thought to be etiologically and/ or pathogenetically related. One of the most frequent sign of these syndromes is the cleft lip and/or cleft palate. It is estimated that 30% of cleft cases are syndromic and conversely, therefore, approximately 70% are non-syndromic. Oral clefts are among the most widely known and com…
ONJ in osteometabolic patients: NO guilty verdict for teeth extraction
2018
The aim of this study is to evaluate retrospectively the impact of some variables on the risk of oNJ onset in osteometabolic non-cancer patients by logistic regression analyses.
Osteonecrosis of the jaw prevention in oncological patients: preliminary results from a teledentistry sicilian project
2019
Bioinformatics analysis of TP53 gene in head and neck squamous cell carcinoma patients from the cancer genome atlas
2019
PREVENTION OF THE DRUG-RELATED OSTEONECROSIS OF THE JAW (ONJ): PRELIMINARY DATA OF THE PROMaF PROTOCOL
2018
Stomatitis and vR-TkI: a review of current literature in 4369 patients
2018
the following review was performed to answer to the question “What is the rate of incidence of oral stomatitis in patients treated with VegF tKis?”