0000000000444789
AUTHOR
Ernst Lebenstedt
Struktur-Wirkungs-Beziehungen bei Histaminanaloga, 12 Mitt.: Imidazo[4,5-g]chinoline
Es werden zwei Wege zur Darstellung des Heterotrizyklus Imidazo[4,5-g]chinolin (8b) sowie zwei seiner partiell reduzierten Derivate 5,6,7,8-Tetrahydro-imidazo[4,5-g]chinolin (8c) und 4,4a,5,6,7,8,8a,9-Octahydro-imidazo[4,5-g]chinolin (8d) beschrieben. Imidazo[4,5-g]quinolines. Two ways for the preparation of the heterotricycle imidazo[4,5-g]quinoline (8b) and two of its partially reduced derivatives, 5,6,7,8-tetrahydro-imidazo[4,5-g]quinoline (8c) and 4,4a,5,6,7,8,8a,9-octahydro-imidazo[4,5-g]quinoline (8d), are described.
Struktur-Wirkungs-Beziehungen bei Histaminanaloga, 5. Mitt. Imidazo[4,5-h]isochinoline
Es werden zwei Wege zur Darstellung des neuen Heterotricyclus Imidazo[4,5-h]isochinolin (7a) sowie zwei seiner partiell hydrierten Derivate 6, 7, 8, 9-Tetrahydro-imidazo[4,5-h]isochinolin (7b) und 4,5,5a,6,7,8,9,9a-Octahydro-imidazo-[4,5-h]isochinolin (7c) beschrieben. Imidazo[4,5-h]isoquinolines Two ways for the preparation of the new heterotricycle imidazo[4,5-h]isoquinoline (7a) and two of its partially reduced derivatives, 6,7,8,9-tetrahydro-imidazo[4,5-h]isoquinoline (7b) and 4,5,5a,6,7,8,9,9a-octahydro-imidazo[4,5-h]isoquinoline (7c), are described.
Struktur-Wirkungsbeziehungen bei Histaminanaloga, 14. Mitt. 4-Aminomethyl-benzimidazole und 9-Amino-naphth[1,2-d]imidazole
Es wird die Darstellung der bicyclischen Histaminanaloga 4-Aminomethyl-benzimidazol (3a) und 4-Aminomethyl-4,5,6,7-tetrahydro-benzimidazol (3b) sowie der tricyclischen Analoga 9-Amino-6,7,8,9-tetrahydro-naphth[1,2-d]imidazol (6b) und 9-Amino-4,5,5a,6,7,8,9,9a-octahydro-naphth[1,2-d]imidazol (6c) beschrieben. 4-(Aminomethyl)benzimidazoles and 9-Aminonaphth[1,2-d]imidazoles Syntheses of the bicyclic histamine analogues 4-(aminomethyl)benzimidazole (3a) and 4-aminomethyl-4,5,6,7-tetrahydrobenzimidazole (3b) and of the tricyclic analogues 9-amino-6,7,8,9-tetrahydronaphth[1,2-d]imidazole (6b) and 9-amino-4,5,5a,6,7,8,9,9a-octahydronaphth[1,2-d]-imidazole (6c) are described.