0000000000445097

AUTHOR

Eric Caudron

showing 2 related works from this author

Bone-Targeted Cisplatin-Complexed Poly(γ-benzyl-L-glutamate)-Poly(glutamic acid) Block Polymer Nanoparticles: An Electrochemical Approach

2015

The voltammetric response of different osteotropic multifunctional nanoparticles based on cisplatin-complexed poly(γ-benzyl-L-glutamate)–poly(glutamic acid) block polymer (CDDP-PBLG-b-PGlu) copolymer, with or without poly(γ-benzyl-L-glutamate)–poly(ethylene glycol) block polymer (PBLG-b-PEG), and having bone-targeting properties is studied at biologically relevant pH. Significant differences in the cisplatin-centered voltammetric signals allow monitoring of the association of cisplatin to nanoparticles as well as release kinetics from them, in agreement with atomic absorption spectroscopy data. Electrochemical studies reveal that the cisplatin association is significant only if the proporti…

Cisplatinchemistry.chemical_classificationMaterials scienceKineticsNanoparticlePolymerGlutamic acidElectrochemistryCatalysischemistry.chemical_compoundchemistryElectrochemistryCopolymermedicineOrganic chemistryEthylene glycolmedicine.drugNuclear chemistryChemElectroChem
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Reactive Element (Y,Ce) Effect on Stresses Determined In-Situ during Iron Oxidation at 800°C

2001

In-situ stress determinations by X-ray diffraction have been performed during pure iron oxidation (p(O 2 ) = 2 x 10 -3 Pa, T = 800°C). On yttrium implanted specimens the stress level is close to zero before oxidation. On CeO 2 coated specimens, the initial compressive stress due to surface polishing is not modified by the coating. During oxidation, the in-situ compressive stress value determined in the Fe (1-x) O scale, is not strongly dependent upon the reactive element nature. Nevertheless, the stress evolution during cooling and residual stresses determined after cooling to room temperature are very different. Blank and CeO 2 coated specimens show relatively high compressive stresses whe…

Materials scienceMechanical EngineeringHigh-temperature corrosionMetallurgyPolishingchemistry.chemical_elementYttriumengineering.materialCondensed Matter PhysicsStress (mechanics)Compressive strengthchemistryCoatingMechanics of MaterialsResidual stressUltimate tensile strengthengineeringGeneral Materials ScienceComposite materialMaterials Science Forum
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