0000000000447726

AUTHOR

Biao Wang

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Whole genome sequencing of the black grouse (Tetrao tetrix): reference guided assembly suggests faster-Z and MHC evolution

2014

Background The different regions of a genome do not evolve at the same rate. For example, comparative genomic studies have suggested that the sex chromosomes and the regions harbouring the immune defence genes in the Major Histocompatability Complex (MHC) may evolve faster than other genomic regions. The advent of the next generation sequencing technologies has made it possible to study which genomic regions are evolutionary liable to change and which are static, as well as enabling an increasing number of genome studies of non-model species. However, de novo sequencing of the whole genome of an organism remains non-trivial. In this study, we present the draft genome of the black grouse, wh…

Tetrao tetrixMaleGenome evolutionBiologyGenomePolymorphism Single NucleotideChromosomesBirdsEvolution MolecularMajor Histocompatibility ComplexGene densityGeneticsAnimalsGenetikGenome sizeRepetitive Sequences Nucleic AcidGeneticsComparative genomicsWhole genome sequencingteeriGenomeComputational BiologyHigh-Throughput Nucleotide SequencingMolecular Sequence AnnotationGenome projectGenomicsEvolutionary biologyReference genomeBiotechnologyResearch ArticleBMC Genomics
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