0000000000455624

AUTHOR

Anne Buschmann

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Impact of vCJD on blood supply.

2007

Variant Creutzfeldt-Jakob disease (vCJD) is an at present inevitably lethal neurodegenerative disease which can only be diagnosed definitely post mortem. The majority of the approximately 200 victims to date have resided in the UK where most contaminated beef materials entered the food chain. Three cases in the UK demonstrated that vCJD can be transmitted by blood transfusion. Since BSE and vCJD have spread to several countries outside the UK, it appears advisable that specific risk assessments be carried out in different countries and geographic areas. This review explains the approach adopted by Germany in assessing the risk and considering precautionary measures. A fundamental premise is…

medicine.medical_specialtyBlood transfusionBovine spongiform encephalopathymedicine.medical_treatmentSpecific riskBioengineeringBlood Component TransfusionBlood DonorsDiseaseApplied Microbiology and BiotechnologyCreutzfeldt-Jakob SyndromeBlood Component TransfusionEnvironmental healthGermanymental disordersmedicineBlood-Borne PathogensAnimalsHumansLeukapheresisPharmacologyGeneral Immunology and Microbiologybusiness.industryIncidencePatient SelectionTransfusion ReactionGeneral MedicineRuminantsmedicine.diseasenervous system diseasesSurgeryEncephalopathy Bovine SpongiformPopulation dataBlood supplyCattleRisk assessmentbusinessBiotechnologyBiologicals : journal of the International Association of Biological Standardization
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