0000000000459519

AUTHOR

G Hess

showing 2 related works from this author

Chirurgie und AIDS

2009

medicine.medical_specialtyText miningAcquired immunodeficiency syndrome (AIDS)business.industryGeneral surgerymedicineMEDLINEGeneral MedicineSurgical proceduresbusinessmedicine.diseaseDMW - Deutsche Medizinische Wochenschrift
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The effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) on hepatitis B vaccination in haemodialysis patients.

1996

Haemodialysis patients often fail to respond to hepatitis B vaccination. In this pilot study, 15 patients previously non-responsive to at least three 40 micrograms doses of hepatitis B vaccine were given 0.5, 5 or 10 micrograms kg-1 granulocyte-macrophage colony-stimulating factor (GM-CSF) subcutaneously 24 h prior to booster vaccination with a hepatitis B vaccine. Seven of the 15 patients developed antibody to hepatitis B surface antigen (HBsAb) (35-7240 IU L-1) upon initial vaccination with GM-CSF and two of four individuals responded with low HBsAb titres of 15 and 60 IU L-1 when revaccinated with hepatitis B surface antigen (HBsAg) and twice the dose of GM-CSF. The application of GM-CSF…

MaleHBsAgHepatitis B vaccinemedicine.medical_treatmentmedicine.disease_causeAdjuvants ImmunologicRenal DialysisVirologyMedicineHumansHepatitis B VaccinesHepatitis B AntibodiesAdverse effectAgedHepatitis B virusHepatitis B Surface AntigensHepatologybiologybusiness.industryGranulocyte-Macrophage Colony-Stimulating FactorImmunosuppressionHepatitis BMiddle Agedmedicine.diseaseHepatitis BVaccinationInfectious DiseasesImmunologybiology.proteinFemaleAntibodyHypotensionbusinessJournal of viral hepatitis
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