Fluorescent-Cavity Host: An Efficient Probe to Study Supramolecular Recognition Mechanisms
Using fluorometry to study the interactions between guests and host cavities is often challenging, especially for hosts with small cavities because the fluorophore may not be close to the binding site. Therefore, it is critical to overcome this hurdle to broaden the applicability of fluorometry in supramolecular chemistry. Herein, we designed a fluorescent-cavity host (H1) by conjugating the binding site of a pillar[5]arene cavity and studied its host-guest recognition mechanism in the cavity. Distinct fluorescent responses of H1 were observed for cyano homologues: the fluorescence was enhanced for succinonitrile but quenched for malononitrile. Such an unusual phenomenon with such subtle di…
CCDC 1811268: Experimental Crystal Structure Determination
Related Article: Wei Cui, Lingyun Wang, Linxian Xu, Guozhen Zhang, Herbert Meier, Hao Tang, Derong Cao|2018|J.Phys.Chem.Lett.|9|1047|doi:10.1021/acs.jpclett.8b00037