0000000000462867
AUTHOR
Lorand Kiss
Fluorine-containing functionalized cyclopentene scaffolds through ring contraction and deoxofluorination of various substituted cyclohexenes
The fluorination of some highly‐functionalized cyclopentene derivatives, obtained from various substituted cyclohexenes through a ring‐opening/ring‐contraction procedure, has been investigated. The transformations were found to be highly substrate dependent, and led to the formation of various functionalized alicyclic compounds or heterocycles containing allyl difluoride or vinyl fluoride moieties. peerReviewed
Stereocontrolled synthesis of fluorine-containing piperidine γ-amino acid derivatives
An efficient synthetic approach for the construction of fluorine‐containing piperidine γ‐amino acid derivatives has been developed. The synthetic concept was based on oxidative ring opening of an unsaturated bicyclic γ‐lactam (Vince‐lactam) through its ring C=C bond, followed by double reductive amination of the diformyl intermediate performed with various fluoroalkylamines. The method has been extended towards the access of alkylated and perfluoroalkylated substances and for γ‐lactam derivatives. The transformations proceeded with stereocontrol: the configuration of the stereocenters in the products were predetermined by the configuration of the chiral centers of the starting γ‐lactam. The…
CCDC 914060: Experimental Crystal Structure Determination
Related Article: Lorand Kiss, Melinda Nonn, Reijo Sillanpaa, Santos Fustero, Ferenc Fulop|2013|Beilstein J.Org.Chem.|9|1164|doi:10.3762/bjoc.9.130
CCDC 914059: Experimental Crystal Structure Determination
Related Article: Lorand Kiss, Melinda Nonn, Reijo Sillanpaa, Santos Fustero, Ferenc Fulop|2013|Beilstein J.Org.Chem.|9|1164|doi:10.3762/bjoc.9.130
CCDC 914062: Experimental Crystal Structure Determination
Related Article: Lorand Kiss, Melinda Nonn, Reijo Sillanpaa, Santos Fustero, Ferenc Fulop|2013|Beilstein J.Org.Chem.|9|1164|doi:10.3762/bjoc.9.130
CCDC 914061: Experimental Crystal Structure Determination
Related Article: Lorand Kiss, Melinda Nonn, Reijo Sillanpaa, Santos Fustero, Ferenc Fulop|2013|Beilstein J.Org.Chem.|9|1164|doi:10.3762/bjoc.9.130