0000000000464063

AUTHOR

Thomas Langer

showing 6 related works from this author

Complete Genome Sequence of a New Clostridium sp. Isolated from Anaerobic Digestion and Biomethanation

2020

Here, we present the genome sequence and annotation of the bacterial strain HV4-5-A1G, a potentially new Clostridium species. Based on its genomic data, this strain may act as a keystone microorganism in the hydrolysis of complex polymers, as well as in the different acidogenesis and acetogenesis steps during anaerobic digestion.

Genome SequencesMicrobiology Resource Announcements
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Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032…

2018

Geburtshilfe und Frauenheilkunde 78(11), 1056-1088 (2018). doi:10.1055/a-0646-4630

medicine.medical_specialtyAdvanced breastPsychological interventionGuideline/LeitlinieSystemic therapymetastasiertes Mammakarzinomprimary breast cancer03 medical and health sciences0302 clinical medicineBreast cancerbreast cancerMaternity and MidwiferyBrustkrebsMedicineprimäres Mammakarzinom030212 general & internal medicineGebFra ScienceIntensive care medicineLeitlinietherapybusiness.industryTumor biologyObstetrics and GynecologyCancerGuidelinemedicine.diseaseMetastatic breast cancerddc:030220 oncology & carcinogenesismetastatic breast cancerbusinessTherapieguideline
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Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032…

2018

62. Kongress der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe, DGGG'18, Berlin, Germany, 31 Oct 2018 - 3 Nov 2018; Geburtshilfe und Frauenheilkunde 78(10), 927-948 (2018). doi:10.1055/a-0646-4522 special issue: "62. Kongress der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe, DGGG'18, Berlin, 31.10 – 03.11.2018 : Frauenheilkunde im Fokus: wissenschaftlich fundiert und der Qualität verpflichtet"

medicine.medical_specialtydiagnosisPsychological interventionComputed tomographyDiseaseGuideline/LeitlinieMammakarzinom03 medical and health sciencesbreast cancerDiagnostik0302 clinical medicineBreast cancerMaternity and Midwiferyfollow-upmedicineMammographyMedical physicsGebFra Science030212 general & internal medicinemedicine.diagnostic_testbusiness.industryscreeningObstetrics and GynecologyCancerGuidelinemedicine.diseaseddc:030220 oncology & carcinogenesisFrüherkennungRichtlinieNachsorgebusinessguidelineSystematic searchGeburtshilfe und Frauenheilkunde
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Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein.

2021

Heart development relies on PTMs that control cardiomyocyte proliferation, differentiation and cardiac morphogenesis. We generated a map of phosphorylation sites during the early stages of cardiac postnatal development in mice; we quantified over 10,000 phosphorylation sites and 5000 proteins that were assigned to different pathways. Analysis of mitochondrial proteins led to the identification of PGC-1- and ERR-induced regulator in muscle 1 (PERM1), which is specifically expressed in skeletal muscle and heart tissue and associates with the outer mitochondrial membrane. We demonstrate PERM1 is subject to rapid changes mediated by the UPS through phosphorylation of its PEST motif by casein ki…

0301 basic medicineProteomicsOrganogenesisMFN2Muscle ProteinsP70-S6 Kinase 1030204 cardiovascular system & hematologyMitochondrionMitochondria Heart03 medical and health sciencesMice0302 clinical medicineCa2+/calmodulin-dependent protein kinaseAnimalsMolecular BiologyMitochondrial transportMice KnockoutChemistryMyocardiumPhosphoproteomicsMembrane ProteinsHeartLipid MetabolismPhosphoproteinsSolute carrier familyCell biology030104 developmental biologyMitochondrial MembranesPhosphorylationCardiology and Cardiovascular MedicineJournal of molecular and cellular cardiology
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Complete genome sequence of a new Bacteroidaceae bacterium isolated from anaerobic biomass digestion

2019

Here, we present the genome sequence and annotation of HV4-6-C5C, a bacterial strain isolated from a mesophilic two-stage laboratory-scale leach bed biogas reactor system. Strain HV4-6-C5C may represent a new genus of the family Bacteroidaceae and may have a key role in acidogenesis and acetogenesis steps during anaerobic biomass digestion.

Whole genome sequencing0303 health sciencesAcidogenesisbiologyChemistry030302 biochemistry & molecular biologyBiomassbiology.organism_classification7. Clean energycomplex mixtures6. Clean water03 medical and health sciencesImmunology and Microbiology (miscellaneous)BiochemistryBiogasAcetogenesisGeneticsMolecular BiologyBacteroidaceaeBacteria030304 developmental biologyMesophile
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Complete Genome Sequence of a New Ruminococcaceae Bacterium Isolated from Anaerobic Biomass Hydrolysis

2018

ABSTRACT A new Ruminococcaceae bacterium, strain HV4-5-B5C, participating in the anaerobic digestion of grass, was isolated from a mesophilic two-stage laboratory-scale leach bed biogas system. The draft annotated genome sequence presented in this study and 16S rRNA gene sequence analysis indicated the affiliation of HV4-5-B5C with the family Ruminococcaceae outside recently described genera.

anaerobic digestion0301 basic medicine570Ruminococcaceae030106 microbiology610BiomassBiologyArticle03 medical and health sciencesHydrolysisBiogasbacterial genomeBotanyGeneticsProkaryotesMolecular BiologyWhole genome sequencingwhole genome sequencingnonhumanmicrobial biomassbacterial strain16S ribosomal RNAAnaerobic digestion030104 developmental biologyhydrolysisAnaerobic exerciseMesophileGenome Announcements
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