0000000000465362

AUTHOR

Zoé Pochon

showing 2 related works from this author

Genomic Data from an Ancient European Battlefield Indicates On-Going Strong Selection on a Genomic Region Associated with Lactase Persistence Over th…

2020

Lactase persistence (LP), the continued expression of lactase into adulthood, is the most strongly selected single gene trait over the last 10,000 years in multiple human populations. It has been posited that the primary allele causing LP among Eurasians, rs4988235*T (Enattah et al. 2008), only rose to appreciable frequencies during the Bronze and Iron Ages (Mathieson et al 2015; Olalde et al. 2018), long after humans started consuming milk from domesticated animals. This rapid rise has been attributed to an influx of peoples from the Pontic-Caspian steppe that began around 5,000 years ago (Allentoft et al. 2015; Furholt et al. 2016). We investigate the spatiotemporal spread of LP through a…

geography050208 financegeography.geographical_feature_categorySteppemedicine.medical_treatment05 social sciencesZoologyPopulation geneticsLactaseengineering.materialLactase persistenceBronze AgeIron Age0502 economics and businessengineeringmedicine050207 economicsBronzeDomesticationSSRN Electronic Journal
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Low Prevalence of Lactase Persistence in Bronze Age Europe Indicates Ongoing Strong Selection over the Last 3,000 Years

2020

Lactase persistence (LP), the continued expression of lactase into adulthood, is the most strongly selected single gene trait over the last 10,000 years inmultiple human populations. It has been posited that the primary allele causing LP among Eurasians, rs4988235-A [1], only rose to appreciable frequencies during the Bronze and Iron Ages [2, 3], long after humans started consuming milk from domesticated animals. This rapid rise has been attributed to an influx of people from the Pontic-Caspian steppe that began around 5,000 years ago [4, 5]. We investigate the spatiotemporal spread of LP through an analysis of 14 warriors from the Tollense Bronze Age battlefield in northern Germany ( 3,20…

AdultMale0301 basic medicineSteppemedicine.medical_treatmentBiologyengineering.materialDNA MitochondrialWhite PeopleGeneral Biochemistry Genetics and Molecular BiologyYoung Adult03 medical and health sciences0302 clinical medicineGene FrequencyBronze AgeLactase persistenceHuman population geneticsmedicineHumansDNA AncientSelection GeneticBronzeDomesticationancient DNALactasegeographygeography.geographical_feature_categoryLactaseBody RemainsEuropeLactase persistence030104 developmental biologyIron AgeengineeringFemaleGeneral Agricultural and Biological Sciences030217 neurology & neurosurgeryDemography
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