0000000000465603

AUTHOR

Etienne Daguindau

showing 3 related works from this author

The rise and the fall of a Pseudomonas aeruginosa endemic lineage in a hospital

2021

The biological features that allow a pathogen to survive in the hospital environment are mostly unknown. The extinction of bacterial epidemics in hospitals is mostly attributed to changes in medical practice, including infection control, but the role of bacterial adaptation has never been documented. We analysed a collection of Pseudomonas aeruginosa isolates belonging to the Besançon Epidemic Strain (BES), responsible for a 12year nosocomial outbreak, using a genotype-to-phenotype approach. Bayesian analysis estimated the emergence of the clone in the hospital 5 years before its opening, during the creation of its water distribution network made of copper. BES survived better than the refe…

DNA Bacterialparallel evolutionLineage (genetic)Genomic IslandsPathogens and EpidemiologyBiologymedicine.disease_causeAmoeba (operating system)Disease OutbreaksMicrobiology03 medical and health sciencesAntibiotic resistanceDrug Resistance Multiple BacterialGenomic islandbacterial pathogensmedicineHumansPseudomonas InfectionsPathogenGenome size[SDV.MP] Life Sciences [q-bio]/Microbiology and ParasitologyResearch Articles030304 developmental biology0303 health sciencesoutbreak030306 microbiologyPseudomonas aeruginosahigh-risk cloneOutbreakBayes TheoremSequence Analysis DNAGeneral MedicineHospitals3. Good healthPhenotype[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyPseudomonas aeruginosa
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Persistent Coronavirus Disease 2019 (COVID-19) in an Immunocompromised Host Treated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-S…

2022

International audience; No abstract available

Microbiology (medical)0303 health sciences2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)030306 microbiologybusiness.industryHost (biology)medicine.drug_classSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[SDV]Life Sciences [q-bio]Monoclonal antibodyVirology03 medical and health sciences0302 clinical medicineInfectious DiseasesMedicine030212 general & internal medicinebusiness
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The rise and the fall of a Pseudomonas aeruginosa epidemic lineage in a hospital

2020

AbstractThe biological features that allow a pathogen to survive in the hospital environment are mostly unknown. The extinction of bacterial epidemics in hospitals is mostly attributed to changes in medical practice, including infection control, but the role of bacterial adaptation has never been documented. We analyzed a collection of Pseudomonas aeruginosa isolates belonging to the Besançon Epidemic Strain (BES), responsible for a 12-year nosocomial outbreak, using a genotype-to-phenotype approach. Bayesian analysis estimated the emergence of the clone in the hospital five years before its opening, during the creation of its water distribution network made of copper. BES survived better t…

Genome evolutionAntibiotic resistancePseudomonas aeruginosaGenomic islandmedicineOutbreakBacterial genome sizeBiologymedicine.disease_causeGenome sizePathogenMicrobiology
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