0000000000465902
AUTHOR
Giulio Perugi
Real-world evidence from a European cohort study of patients with treatment resistant depression : Baseline patient characteristics
Journal of affective disorders 283, 115-122 (2021). doi:10.1016/j.jad.2020.11.124
Real-world evidence from a European cohort study of patients with treatment resistant depression: Treatment patterns and clinical outcomes.
Abstract Background Treatment resistant depression (TRD) characterizes a subgroup of 10–30% of patients with major depressive disorder, and is associated with considerable morbidity and mortality. A consensus treatment for TRD does not exist, which often leads to wide variations in treatment strategies. Real-world studies on treatment patterns and outcomes in TRD patients in Europe are lacking and could help elucidate current treatment strategies and their efficacy. Methods This non-interventional cohort study of patients with TRD (defined as treatment failure on ≥2 oral antidepressants given at adequate dose and duration) with moderate to severe depression collected real-world data on trea…