0000000000466151

AUTHOR

Salvador Tranche

showing 2 related works from this author

Urinary albumin excretion and glomerular filtration rate across the spectrum of glucose abnormalities in essential hypertension.

2006

The objective of this study was to assess the relationship between urinary albumin excretion (UAE) and GF across the spectrum of the glucose metabolism abnormalities in a large population of patients with hypertension. The Microaluminuria en Pacientes con Glucemia Basal Alterada (MAGAL) is a multicenter, cross-sectional study that was carried out by 1723 primary care physicians. A total of 6227 patients with essential hypertension (in three groups: [1] normal fasting glucose100 mg/dl, [2] impaired fasting glucoseor =100 to 126 mg/dl, and [3] type 2 diabetes) were analyzed in this substudy. GFR was estimated by using the Modification of Diet in Renal Disease (MDRD) abbreviated equation. A si…

Malemedicine.medical_specialtyRenal functionType 2 diabetesEssential hypertensionGastroenterologyExcretionCohort Studieschemistry.chemical_compoundInternal medicineDiabetes mellitusmedicineAlbuminuriaHumansRenal InsufficiencyAgedCreatinineProteinuriabusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseImpaired fasting glucoseEndocrinologyCross-Sectional StudiesGlucosechemistryDiabetes Mellitus Type 2NephrologyHyperglycemiaHypertensionFemalemedicine.symptombusinessGlomerular Filtration RateJournal of the American Society of Nephrology : JASN
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Riesgo de interacciones farmacológicas por la coadministración de estatinas con fármacos metabolizados por la isoenzima 3A4 del citocromo P450: estud…

2014

Resumen Fundamento y objetivo Las estatinas son farmacos seguros, pero con un elevado riesgo de interacciones farmacologicas. El objetivo del estudio fue evaluar la prevalencia de interacciones potenciales en la isoenzima 3A4 del citocromo P450 (CYP3A4), en una amplia muestra de pacientes tratados con estatinas, y determinar los factores asociados, tanto del paciente como del medico prescriptor. Pacientes y metodo Estudio observacional, transversal, de base poblacional. Fueron seleccionados 7.880 sujetos en tratamiento con estatinas. Se recogieron datos referentes a los pacientes y a los 1.681 medicos participantes. Resultados Un 59% de los pacientes recibia estatinas metabolizadas por el C…

business.industryMedicineGeneral MedicinebusinessHumanitiesMedicina Clínica
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