0000000000470475
AUTHOR
P. Neumann
Behandlung der ausgeprägten Pubertätsgynäkomastie mit Tamoxifen
Based on the good results of another author 10 boys with marked pubertal gynecomastia were treated with the antioestrogen Tamoxifen (Nolvadex) at a dose of 20-40 mg/d orally for 2-12 months. In most cases the gynecomastia decreased totally, only two patients experienced palpable subareolar glandular tissue at the end of therapy. Side effects were not noted. During therapy levels of estradiol and testosteron increased, with a more pronounced elevation of estradiol. Basal values of LH and FSH remained nearly unchanged, but LH showed an increased response to LH-RH, which could be explained by the antioestrogenic effect of Tamoxifen at the hypothalamic level. The reduction of breast size in spi…
CCDC 178153: Experimental Crystal Structure Determination
Related Article: M.Zaidlewicz, W.Sokol, A.Wojtczak, P.Neumann, M.Nissinen|2002|Tetrahedron Lett.|43|3525|doi:10.1016/S0040-4039(02)00587-7
CCDC 178064: Experimental Crystal Structure Determination
Related Article: M.Zaidlewicz, W.Sokol, A.Wojtczak, P.Neumann, M.Nissinen|2002|Tetrahedron Lett.|43|3525|doi:10.1016/S0040-4039(02)00587-7
CCDC 178152: Experimental Crystal Structure Determination
Related Article: M.Zaidlewicz, W.Sokol, A.Wojtczak, P.Neumann, M.Nissinen|2002|Tetrahedron Lett.|43|3525|doi:10.1016/S0040-4039(02)00587-7