0000000000473774

AUTHOR

M Biasini

showing 11 related works from this author

Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study

2020

Background The aims of this study were to provide data on the safety of head and neck cancer surgery currently being undertaken during the coronavirus disease 2019 (COVID-19) pandemic. Methods This international, observational cohort study comprised 1137 consecutive patients with head and neck cancer undergoing primary surgery with curative intent in 26 countries. Factors associated with severe pulmonary complications in COVID-19-positive patients and infections in the surgical team were determined by univariate analysis. Results Among the 1137 patients, the commonest sites were the oral cavity (38%) and the thyroid (21%). For oropharynx and larynx tumors, nonsurgical therapy was favored in…

Cancer ResearchInfectious Disease TransmissionSettore MED/29 - CHIRURGIA MAXILLOFACCIALEInternational CooperationSettore MED/19 - Chirurgia Plasticacoronavirusmedicine.disease_causePatient-to-Professionalsurgery0302 clinical medicine80 and over030212 general & internal medicineCoronavirusAged 80 and overUnivariate analysisCOMPLICATIONSOUTCOMESIncidence (epidemiology)Middle AgedOncologyHead and Neck Neoplasms030220 oncology & carcinogenesiscoronavirus disease 2019 (COVID-19)Cohort studyAdultmedicine.medical_specialtyInfectious Disease Transmission Patient-to-ProfessionalCritical Care03 medical and health sciencesPatient safetyYoung AdultSettore MED/28 - Malattie OdontostomatologichemedicineHumansReconstructive Surgical Proceduressevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PandemicsPersonal Protective EquipmentAgedNeoplasm StagingSurgeonsSurgical teambusiness.industryHead and neck cancerCancerCOVID-19Plastic Surgery ProceduresCAREmedicine.disease3126 Surgery anesthesiology intensive care radiologySurgerycoronavirucoronavirus; coronavirus disease 2019 (COVID-19); head and neck cancer; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); surgeryhead and neck cancerbusiness
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Measurement of Semileptonic B Decays into Orbitally Excited Charmed Mesons

2009

We present a study of B decays into semileptonic final states containing charged and neutral D-1(2420) and D-2*(2460). The analysis is based on a data sample of 208 fb(-1) collected at the Y(4S) resonance with the BABAR detector at the PEP-II asymmetric-energy B factory at SLAC. With a simultaneous fit to four different decay chains, the semileptonic branching fractions are extracted from measurements of the mass difference Delta m = m(D**) - m(D) distribution. Product branching fractions are determined to be B(B+ -> D(1)(0)l(+)nu(l)) x B(D-1(0) -> D*+pi(-)) = (2.97 +/- 0.17 +/- 0.17) x 10(-3), B(B+ -> D-2*l(+)nu(e)) x B(D-2*(0) -> D(*)+pi(-)) = (2.29 +/- 0.23 +/- 0.21) x 10(-3), B(B-0 -> D…

Semileptonic decayParticle physicsMesonBABARHadronAnalytical chemistryGeneral Physics and AstronomyFOS: Physical sciencesB meson01 natural sciencesPARTICLE PHYSICS; PEP2; BABARHigh Energy Physics - ExperimentParticle decayHigh Energy Physics - Experiment (hep-ex)Pion0103 physical sciencesPEP2[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]B meson010306 general physicsB meson; CP violationPhysics010308 nuclear & particles physicsBranching fractionParticle physicsBABAR detectorHEPB-factoryCP violationBaBarPARTICLE PHYSICSFísica de partículesExperimentsPHYSICAL REVIEW LETTERS
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Elective Cancer Surgery in COVID-19-Free Surgical Pathways during the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

2020

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a …

MaleCancer ResearchOutcome AssessmentInternational CooperationSettore MED/18 - CHIRURGIA GENERALESettore MED/19 - Chirurgia Plastica030230 surgeryAged; Aged 80 and over; COVID-19; Cohort Studies; Critical Care; Elective Surgical Procedures; Epidemics; Female; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Neoplasms; Outcome Assessment Health Care; Postoperative Complications; SARS-CoV-2Cohort Studies0302 clinical medicineOperating theaterPostoperative Complicationscohort studiesNeoplasmsHealth caremiddle agedOutcome Assessment Health Care80 and overMedicineLungCancerCOVID-19/epidemiologyAged 80 and overOUTCOMESManchester Cancer Research CentrePulmonary ComplicationORIGINAL REPORTSMiddle AgedagedOncologyElective Surgical Procedures030220 oncology & carcinogenesisPneumonia & InfluenzaFemalePatient SafetyElective Surgical ProcedureLife Sciences & Biomedicine6.4 SurgeryCohort studyHumanmedicine.medical_specialtyelective surgical procedures/methodsLogistic ModelCritical CareAged; Aged; 80 and over; COVID-19; Cohort Studies; Critical Care; Elective Surgical Procedures; Epidemics; Female; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Neoplasms; Outcome Assessment; Health Care; Postoperative Complications; SARS-CoV-2Clinical SciencesOncology and CarcinogenesisEpidemic[SDV.CAN]Life Sciences [q-bio]/Cancer-.cancer surgery ; COVID-19 ; SARS-CoV-2 pandemicepidemicsCOVIDSurg CollaborativeNOoutcome assessment health care/methods03 medical and health sciencesmaleSettore MED/28 - Malattie OdontostomatologicheClinical ResearchHumans1112 Oncology and CarcinogenesisOncology & CarcinogenesisElective surgeryEpidemicsElective Cancer Surgery in SARS-CoV-2 Elective Cancer Surgery in COVID-19 covid 19 sars-cov-2AgedScience & TechnologyElective Surgical Procedurebusiness.industrySARS-CoV-2PreventionResearchInstitutes_Networks_Beacons/mcrcEvaluation of treatments and therapeutic interventionsCOVID-191103 Clinical SciencesPneumoniaOdds ratiomedicine.diseaseHealth CarePneumoniaGood Health and Well Beingneoplasms/surgeryLogistic Modelscritical care/methodsEmergency medicinepostoperative complications/prevention & controlNeoplasmPostoperative ComplicationCohort Studiebusinessaged 80 and overSARS-CoV-2/physiologylogistic models
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Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic

2021

Association of Surgeons in Training Surgical Summit, online, 17 Oct 2020 - 17 Oct 2020 2021 Virtual Annual Meeting / Surgical Research Society, online, 24 Mar 2021 - 25 Mar 2021, National Research Collaborative Meeting, online, 10 Dec 2020 - 10 Dec 2020, Royal Australasian College of Surgeons Annual Academic Surgery Conference, online, 5 Nov 2020 - 5 Nov 2020; The British journal of surgery : BJS 108(12), 1448-1464 (2021). doi:10.1093/bjs/znab336

MaleRespiration Artificial/statistics & numerical dataSettore MED/18 - CHIRURGIA GENERALEeducation-Sciences du Vivant [q-bio]/Médecine humaine et pathologieAbdominal NeoplasmPostoperative Complications/mortalityNOsurgeryCohort Studies03 medical and health sciencesCOVID-19; death; SARS-CoV-2; surgery0302 clinical medicinePostoperative ComplicationsdeathHumans030212 general & internal medicinePandemicsAbdominal Neoplasms/surgeryAgedLS7_4COVID-19/mortalityRespiratory Distress SyndromePandemicSARS-CoV-2Respirationsurgical procedures operativemortalitysurgery specialtypandemicspulmonary complicationssars-cov-2covid-19coronavirus pandemicCOVID-19Middle Aged3126 Surgery anesthesiology intensive care radiologyRespiration Artificialsurgical proceduresoperativemortalitysurgery specialtypandemicspulmonary complicationssars-cov-2covid-19coronavirus pandemicAbdominal Neoplasms; Aged; COVID-19; Cohort Studies; Female; Humans; Male; Middle Aged; Pandemics; Postoperative Complications; Respiration Artificial; Respiratory Distress Syndrome; Elective Surgical ProceduresElective Surgical Procedures030220 oncology & carcinogenesisAbdominal NeoplasmsArtificialFemalePostoperative ComplicationCohort Studie[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyRespiratory Distress Syndrome/mortalityHuman
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Search for a muonic dark force at BaBar

2016

Many models of physics beyond the Standard Model predict the existence of new Abelian forces with new gauge bosons mediating interactions between "dark sectors" and the Standard Model. We report a search for a dark boson Z' coupling only to the second and third generations of leptons in the reaction e+e- -> mu+mu- Z', Z' -> mu+mu- using 514 fb-1 of data collected by the BABAR experiment. No significant signal is observed for Z' masses in the range 0.212 - 10 GeV. Limits on the coupling parameter g' as low as 7x10^-4 are derived, leading to improvements in the bounds compared to those previously derived from neutrino experiments.

Particle physicsNuclear and High Energy PhysicsPhysics and Astronomy (miscellaneous)Physics beyond the Standard ModelDark matterBaBar experimentFOS: Physical sciences01 natural sciencesPartícules (Matèria)Standard ModelHigh Energy Physics - ExperimentNONuclear physicsHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]010306 general physicsBosonPhysicsGauge boson010308 nuclear & particles physicshep-exSettore FIS/01 - Fisica SperimentaleHigh Energy Physics::Phenomenologyhep-phHEPHigh Energy Physics - PhenomenologyParticlesDark matter (Astronomy)[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]BaBarMatèria fosca (Astronomia)NeutrinoLepton
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Improved limits on the lepton-flavor violating decays tau(-) -> l(-)l(+)l(-)

2007

A search for the neutrinoless, lepton-flavor violating decay of the tau lepton into three charged leptons has been performed using 376fb-1 of data collected at an e+e- center-of-mass energy around 10.58 GeV with the BABAR detector at the SLAC PEP-II storage rings. In all six decay modes considered, the numbers of events found in data are compatible with the background expectations. Upper limits on the branching fractions are set in the range (4-8)×10-8 at 90% confidence level. © 2007 The American Physical Society.

Particle physicsVIOLATIONMesonElectron–positron annihilationCharged particleGeneral Physics and AstronomyElectron01 natural sciencesNuclear physicsParticle decaySEARCH; LEPTON; FLAVOR; VIOLATION; BABAR; SLACPositronSEARCH0103 physical sciencesFree energyLEPTON010306 general physicsPhysicsVolume fractionMuon010308 nuclear & particles physicsBranching fractionHigh Energy Physics::PhenomenologyParticle physicsBABAR detectorLepton flavorCharged leptonHEPGermanium compoundBaBarHigh Energy Physics::ExperimentParticle detectorSLACFísica de partículesExperimentsFLAVORLepton
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Delaying surgery for patients with a previous SARS-CoV-2 infection

2020

With at least 28 elective million operations delayed during the first three months of the COVID-19 pandemic, the number of patients who will require surgery after a previous SARS-CoV-2 infection is likely to increase rapidly1. Operating on patients with an active perioperative SARS-CoV-2 infection is now known to carry a very high pulmonary complication and mortality rate2. Urgent information is needed to guide whether postponing surgery in patients with a previous SARS-CoV-2 infection leads to a clinical benefit, and the optimal length of delay.

SARS Virus Coronavirus Severe Acute Respiratory Syndrome cancersurgery pandemic infectionSettore MED/06 - Oncologia MedicaSettore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALECOVID-19. Global surgery.Settore MED/19 - Chirurgia PlasticaComorbidity030230 surgeryCovidCOVID-19 / epidemiologysurgery0302 clinical medicineNeoplasms / surgeryNeoplasmsCOVID-19; Comorbidity; Humans; Neoplasms; Surgical Procedures Operative; Pandemics; SARS-CoV-2; Time-to-TreatmentProspective cohort study610 Medicine & healthCOVID-19/epidemiologymedicine.diagnostic_testSurgery sars-cov-2 covid surg surgery pandemic infectionPulmonary ComplicationSARS cov 2Covid19Surgical Procedures Operative / methodsOperativesurgery; Sars-CoV-2Surgical Procedures OperativeSurgery sars-cov-2Neoplasms / epidemiologyCohort studyHumanmedicine.medical_specialtySciences du Vivant [q-bio]/Médecine humaine et pathologieNOTime-to-TreatmentThroat culture03 medical and health sciencesSettore MED/28 - Malattie OdontostomatologichemedicineResearch LetterHumansElective surgeryGeneralPandemicscovid surgSurgical ProceduresPandemicbusiness.industrySARS-CoV-2No key words availablePostoperative complicationCOVID-19Perioperativemedicine.diseaseSurgeryPneumoniaSettore MED/40 - GINECOLOGIA E OSTETRICIANeoplasmSurgical Procedures Operative/methodsSurgerybusinessNeoplasms/epidemiology[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Measurement of the semileptonic branching fraction of the B_{s} meson

2012

We report a measurement of the inclusive semileptonic branching fraction of the B_s meson using data collected with the BaBar detector in the center-of-mass (CM) energy region above the Upsilon(4S) resonance. We use the inclusive yield of phi mesons and the phi yield in association with a high-momentum lepton to perform a simultaneous measurement of the semileptonic branching fraction and the production rate of B_s mesons relative to all B mesons as a function of CM energy. The inclusive semileptonic branching fraction of the B_s meson is determined to be B(B_s to l nu X)=9.5 (+2.5/-2.0)(stat)(+1.1/-1.9)(syst)%, where l indicates the average of e and mu.

Nuclear and High Energy PhysicsParticle physicssemileptonic branching fractionMesonHigh Energy Physics::Latticesemileptonic branching fraction B_s mesonFOS: Physical sciences01 natural sciencesResonance (particle physics)semileptonic Bs-meson decaysHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Mesons (Nuclear physics)B mesonSDG 7 - Affordable and Clean EnergyMesons (Física nuclear)010306 general physicsNuclear Experiment14.40.Nd 13.20.HePhysics/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy010308 nuclear & particles physicsBranching fractionLeptons (Física nuclear)High Energy Physics::PhenomenologyBABAR detectorbranching fraction measurementHEPPACS: 14.40.Nd 13.20.HeBaBar detector at SLAC; semileptonic Bs-meson decays; branching fraction measurementLeptons (Nuclear physics)Yield (chemistry)BaBarB_s mesonHigh Energy Physics::ExperimentBaBar detector at SLACsemileptonic Bs-meson decayLeptonProduction rate
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Searches for B0 decays to combinations of charmless isoscalar mesons

2004

We search for B meson decays into two-body combinations of eta, eta', omega, and phi mesons from 89 million B B-bar pairs collected with the BaBar detector at the PEP-II asymmetric-energy e+e- collider at SLAC. We find the branching fraction BF(B0 -> eta omega) = (4.0^{+1.3}_{-1.2} +- 0.4) x 10^-6 with a significance of 4.3 sigma. For all the other decay modes we set the following 90% confidence level upper limits on the branching fractions, in units of 10^-6 : BF(B0 -> eta eta)<2.8, BF(B0 -> eta eta')<4.6, BF(B0 -> eta' eta')<10, BF(B0 -> eta'omega)<2.8, BF(B0 -> eta phi)<1.0, BF(B0 -> eta' phi)<4.5, BF(B0 -> phi phi)<1.5.

IsoscalarElectron–positron annihilationBABARGeneral Physics and AstronomyQCD FACTORIZATION01 natural sciencesOmega13.25.Hw 11.30.Er 12.15.HhHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)Mathematical modelProbability density function[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]PEP2B mesonNuclear ExperimentQCD FACTORIZATION; STANDARD MODEL; BABAR; SLACPhysicsQuantum chromodynamicsSigmaHamiltonianMonte Carlo methodSensitivity analysiPARTICLE PHYSICSBranching fractionSLACParticle physicsMesonSTANDARD MODELQCD FACTORIZATION STANDARD MODELFOS: Physical sciencesLikelihood distributionPARTICLE PHYSICS; PEP2; BABARSolenoidHigh energy physicNuclear physicsPhysics and Astronomy (all)ElectromagnetismElectromagnetic calorimeterPseudoscalar meson0103 physical sciencesPerturbation technique010306 general physicsCalorimeterError analysi010308 nuclear & particles physicsBranching fractionHEPMagnetic fieldHigh Energy Physics::Experiment
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Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study

2021

This international, prospective, cohort study enrolled 20 006 adult (≥18 years) patients from 466 hospitals in 61 countries with 15 cancer types, who had a decision for curative surgery during the COVID-19 pandemic and were followed up until the point of surgery or cessation of follow-up (Aug 31, 2020). Average national Oxford COVID-19 Stringency Index scores were calculated to define the government response to COVID-19 for each patient for the period they awaited surgery, and classified into light restrictions (index 60). The primary outcome was the non-operation rate (defined as the proportion of patients who did not undergo planned surgery). Cox proportional-hazards regression models wer…

MaleCOVID-19 COVIDSURG COVIDSURG CANCEROutcome AssessmentIMPACTSettore MED/18 - CHIRURGIA GENERALEBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Surgery.surgeryCancer surgeryNeoplasms/classificationBIOMEDICINA I ZDRAVSTVO. Javno zdravstvo i zdravstvena zaštita.Surgical oncologyNeoplasmsAcute careCOVID-19 - epidemiologyOutcome Assessment Health CareMedicine and Health Sciences80 and overGlobal healthtimingProspective StudiesUK610 Medicine & healthProspective cohort studyCOVID-19/epidemiologyCOVIDAged 80 and overBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Oncology.BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Kirurgija.Hazard ratioArticlesMiddle AgedOncologyAdult; Aged; Aged 80 and over; Communicable Disease Control; COVID-19; Female; Humans; Male; Middle Aged; Neoplasms; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; SARS-CoV-2; Time-to-Treatment; Withholding Treatment/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemalecancer surgeryCovid-19Life Sciences & BiomedicineMENTAL-HEALTHmental healthCohort studyHumanAdultmedicine.medical_specialtydelay3122 CancersCOVID-19 - prevention and control610 Medicine & healthCOVIDSurg CollaborativeNOTime-to-TreatmentSDG 3 - Good Health and Well-beingLockdownmedicineHumanscancer1112 Oncology and CarcinogenesisOncology & CarcinogenesisElective surgeryLS7_4Proportional Hazards ModelsAgedScience & Technologybusiness.industrySARS-CoV-2Public healthGeneral surgeryBIOMEDICINE AND HEALTHCARE. Public Health and Health Care.COVID-193126 Surgery anesthesiology intensive care radiologyHealth CareCommunicable Disease Control/legislation & jurisprudenceProspective StudieWithholding TreatmentCOVID-19; delay; SARS-CoV-2; surgery; timing; cancer surgery;COVID-19 ; lockdowns ; cancer surgeryCommunicable Disease ControlBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Onkologija.Proportional Hazards ModelNeoplasmbusiness
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Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pand…

2021

Abstract Background Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. Methods This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. Results Of 8…

Lung DiseasesMalexAcademicSubjects/MED00910COVID-19/diagnosisSettore MED/18 - CHIRURGIA GENERALEneoplasms030230 surgeryminorsurgical proceduresMedical and Health SciencesLung Disease0302 clinical medicinePostoperative Complications030202 anesthesiologyaged; aged 80 and over; COVID-19; elective surgical procedures; female; humans; lung diseases; male; middle aged; Nasopharynx; neoplasms; pandemics; postoperative complications; risk assessment; SARS-CoV-2; COVID-19 nucleic acid testingNeoplasmsNasopharynx80 and over030212 general & internal medicine610 Medicine & healthLungCancerlung diseasesAged 80 and overIncidence (epidemiology)ConfoundingPulmonary ComplicationLung Diseases/*etiologyNeoplasms/surgeryGeneral MedicineMiddle AgedElective Surgical Procedures/adverse effectsOncologyElective Surgical Procedures030220 oncology & carcinogenesisCOVID-19 Nucleic Acid TestingOriginal ArticleFemalePatient SafetyAcademicSubjects/MED00010Elective Surgical Procedure6.4 SurgeryHumanCohort studymedicine.medical_specialtypreoperative caresurgical proceduresCOVID-19 nucleic acid testing.elective surgical proceduresPreoperative careRisk AssessmentArticleCOVIDSurg CollaborativeNO*COVID-19 Nucleic Acid TestingVaccine Related03 medical and health sciencesClinical ResearchBiodefensemedicineNasopharynx/*virologyHumansNasopharynx/virologyElective surgeryAdverse effectPandemicsLS7_4AgedElective Surgical ProcedurePandemicbusiness.industrySARS-CoV-2Surgery Sars Cov2PreventionNo key words availableelectivesurgical proceduresLung Diseases/etiologyEvaluation of treatments and therapeutic interventionsCancerPostoperative complicationoperativenasopharynxsurgery specialtypulmonary complicationscancer surgerysars-cov-2covid-19coronavirus pandemicCOVID-19Odds ratiomedicine.diseaseConfidence intervalSurgeryCOVID-19/*diagnosisEmerging Infectious DiseasesGood Health and Well BeingNeoplasmSurgeryPostoperative Complicationpreoperative caresurgical procedures electivesurgical procedures minorsurgical procedures operativenasopharynxsurgery specialtypulmonary complicationscancer surgerysars-cov-2covid-19coronavirus pandemicElective Surgical Procedures/*adverse effectsbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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