0000000000476609

AUTHOR

C.e. Kleyn

showing 3 related works from this author

Levocetirizine for the treatment of itch in psoriasis patients: An open-label pilot study in a real-world setting.

2019

Itch is the most bothersome symptom in psoriasis, often leading to impaired quality of life. Treatment of psoriasis-induced itch is frequently unsatisfactory as the various therapies employed have a delayed onset of effect. Histamine-1 receptor (H1) antihistamines are not recommended in treatment guidelines as histamine is not considered a key mediator in psoriasis. However, patients using H1 antihistamines frequently report benefits in questionnaire-based studies. To address these contradictions, we examined the short-term effects of levocetirizine, a nonsedating H1 antihistamine, on psoriasis-related itch and itch-related quality of life. In this pilot study, patients with psoriasis-relat…

AdultMalemedicine.medical_specialtyHistamine H1 Antagonists Non-SedatingTime FactorsPilot ProjectsDermatologyLevocetirizine030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineQuality of lifeimmune system diseasesPsoriasisparasitic diseasesotorhinolaryngologic diseasesMedicineEffective treatmentHumansPsoriasisskin and connective tissue diseasesH1 antihistamineDose-Response Relationship Drugbusiness.industryPruritusDelayed onsetGeneral MedicineMiddle Agedmedicine.diseaseDermatologyeye diseasesCetirizineTreatment Outcome030220 oncology & carcinogenesisConcomitantQuality of LifeFemaleOpen labelbusinessmedicine.drugDermatologic therapyREFERENCES
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The relationship between PASI and DLQI with itch, stress, and depression: Do we need additional decision‐making tools in psoriasis?

2019

medicine.medical_specialtyDepressionbusiness.industryMEDLINEDermatologyGeneral Medicinemedicine.diseaseSeverity of Illness IndexQuality of lifePsoriasisSeverity of illnessQuality of LifemedicineHumansPsoriasisPsychiatrybusinessDepression (differential diagnoses)Dermatologic Therapy
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The short‐term effect of levocetirizine on quality of life, stress, and depression in itchy psoriasis patients

2019

AdultHistamine H1 Antagonists Non-Sedatingmedicine.medical_specialtyMEDLINEDermatologyLevocetirizineQuality of life (healthcare)Surveys and QuestionnairesInternal medicinePsoriasisHumansPsoriasisMedicineTerm effectDepression (differential diagnoses)Depressionbusiness.industryPruritusGeneral MedicineMiddle AgedHistamine H1 Antagonistsmedicine.diseaseCetirizineQuality of LifebusinessStress Psychologicalmedicine.drugDermatologic Therapy
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