0000000000478605

AUTHOR

A. Hussein

showing 5 related works from this author

Search for heavy neutrinos in → Decay

2019

In the present work of the PIENU experiment, heavy neutrinos were sought in pion decays π+→μ+ν at rest by examining the observed muon energy spectrum for extra peaks in addition to the expected peak for a light neutrino. No evidence for heavy neutrinos was observed. Upper limits were set on the neutrino mixing matrix |Uμi|2 in the neutrino mass region of 15.7–33.8 MeV/c$^{2}$, improving on previous results by an order of magnitude.

Physics Letters
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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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Improved search for heavy neutrinos in the decay π→eν

2018

A search for massive neutrinos has been made in the decay π+→e+ν. No evidence was found for extra peaks in the positron energy spectrum indicative of pion decays involving massive neutrinos (π→e+νh). Upper limits (90% C.L.) on the neutrino mixing matrix element |Uei|2 in the neutrino mass region 60–135 MeV/c2 were set and are an order of magnitude improvement over previous results.

Physics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaHigh Energy Physics::PhenomenologyHigh Energy Physics::Experiment
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Initial results from the PIENU experiment

2017

The pion branching ratio, $R_{\pi } = \frac { {\Gamma }(\pi ^{+} \rightarrow e^{+} \nu _{e} + \pi ^{+}\rightarrow e^{+} \nu _{e} \gamma )}{\Gamma (\pi ^{+} \rightarrow \mu ^{+} \nu _{\mu } + \pi ^{+} \rightarrow \mu ^{+} \nu _{\mu } \gamma )}$ , provides a sensitive test of lepton universality and constraints on many new physics scenarios. The theoretical uncertainty on the Standard Model prediction of R π is 0.02 %, a factor of twenty smaller than the experimental uncertainty. The analysis of a subset of data taken by the PIENU experiment will be presented. The result, R π = (1.2344 ± 0.0023(s t a t) ± 0.0019(s y s t)) ⋅ 10−4 [1], is consistent with the Standard Model prediction and repres…

PhysicsNuclear and High Energy PhysicsParticle physics010308 nuclear & particles physicsBranching fractionPhysics beyond the Standard ModelHigh Energy Physics::PhenomenologyCondensed Matter Physics01 natural sciencesAtomic and Molecular Physics and OpticsNuclear physicsPion0103 physical sciencesHigh Energy Physics::ExperimentPhysical and Theoretical Chemistry010306 general physicsParticle Physics - ExperimentLepton
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Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study

2019

Background: Results from retrospective studies suggest that use of neuromuscular blocking agents during general anaesthesia might be linked to postoperative pulmonary complications. We therefore aimed to assess whether the use of neuromuscular blocking agents is associated with postoperative pulmonary complications. Methods: We did a multicentre, prospective observational cohort study. Patients were recruited from 211 hospitals in 28 European countries. We included patients (aged ≥18 years) who received general anaesthesia for any in-hospital procedure except cardiac surgery. Patient characteristics, surgical and anaesthetic details, and chart review at discharge were prospectively collecte…

Pulmonary and Respiratory Medicinepulmonary complications muscle relaxants Post-anaesthesia complicationsNeuromuscular Blockadepulmonary complication muscle relaxantneuromuscular block ; postoperative pulmonary complicationbusiness.industryRetrospective cohort studypost-operative pulmonary complicationsNeuromuscular monitoringNeuromuscular Blocking AgentsSugammadexNOAnaesthesia03 medical and health sciences0302 clinical medicine030228 respiratory systemAnesthesiaMedicineGeneral anaesthesiaNeuromuscular Agents030212 general & internal medicineMED/41 - ANESTESIOLOGIAProspective cohort studybusinessmedicine.drug
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