0000000000480281

AUTHOR

U. Frank

showing 2 related works from this author

15. Mainzer Allergie-Workshop 2003

2003

030207 dermatology & venereal diseases03 medical and health sciencesmedicine.medical_specialty0302 clinical medicine030228 respiratory systemOtorhinolaryngologybusiness.industryFamily medicinemedicineImmunology and AllergybusinessAllergo Journal
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The effect of Dextransulfate 500 on the pathogenesis of herpes simplex virus infections in weanling mice

1978

Intraperitoneal (i.p.) injection of Dextran Sulfate (D.S.) 500 during a limited period of time influences the course of herpes simplex-virus-infections. D.S.500 was found to reduce the resistance of mice for some herpes simplex-virus strains (Len, L3-2s, Haase) if given between 16 hours before and 2 hours after i.p. infection. The decrease of resistance could be correlated with an increase of the virus content of liver, spleen, brain and spinal cord. Injection of herpes simplex-virus-specific immune serum counteracted the effect of D.S.500 on the course of infections. Conversely, D.S.500 increased the resistance of mice to another group of herpes simplex-viruses (strains D-316, Thea, DD), i…

medicine.medical_specialtyTime FactorsvirusesWeanlingMice Inbred StrainsSpleenBiologymedicine.disease_causeVirusPathogenesisMicePeritoneal cavityMedical microbiologySpecies SpecificityVirologymedicineAnimalsSimplexvirusMacrophagesDextransHerpes SimplexGeneral MedicineSpinal cordVirologyHerpes simplex virusmedicine.anatomical_structureImmunologyAdsorptionArchives of Virology
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