0000000000481633

AUTHOR

Jacek Wendykier

0000-0001-9954-470x

Determination of boundaries between ranges of high and low gradient of beam profile

Abstract Aim This work addresses the problem of treatment planning system commissioning by introducing a new method of determination of boundaries between high and low gradient in beam profile. Background The commissioning of a treatment planning system is a very important task in the radiation therapy. One of the main goals of this task is to compare two field profiles: measured and calculated. Applying points of 80% and 120% of nominal field size can lead to the incorrect determination of boundaries, especially for small field sizes. Materials and methods The method that is based on the beam profile gradient allows for proper assignment of boundaries between high and low gradient regions …

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Competing species system as a qualitative model of radiation therapy

To examine complex features of tumor dynamics we analyze a competing-species lattice model that takes into account the competition for nutrients or space as well as interaction with therapeutic factors such as drugs or radiation. Our model might be interpreted as a certain prey–predator system having three trophic layers: (i) the basal species that might be interpreted as nutrients; (ii) normal and tumor cells that consume nutrients, and (iii) therapeutic factors that might kill either nutrient, normal or tumor cells. Using a wide spectrum of parameters we examined survival of our species and tried to identify the corresponding dynamical regimes. It was found that the radiotherapy influence…

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Critical behavior of a tumor growth model: directed percolation with a mean-field flavor.

We examine the critical behaviour of a lattice model of tumor growth where supplied nutrients are correlated with the distribution of tumor cells. Our results support the previous report (Ferreira et al., Phys. Rev. E 85, 010901 (2012)), which suggested that the critical behaviour of the model differs from the expected Directed Percolation (DP) universality class. Surprisingly, only some of the critical exponents (beta, alpha, nu_perp, and z) take non-DP values while some others (beta', nu_||, and spreading-dynamics exponents Theta, delta, z') remain very close to their DP counterparts. The obtained exponents satisfy the scaling relations beta=alpha*nu_||, beta'=delta*nu_||, and the general…

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[P149] Beam profile characteristic points designation for off-axis, wedged and FFF beams

Purpose The main aim of this work is the search of characteristic points of a beam profile and application of these points for the TPS commissioning purposes. The comparison between profiles during the commissioning of the treatment planning system is a very important procedure. It is impossible to designate a field size for the off-axis, wedged and FFF beams directly using the definition of the on-axis symmetric field size. This work demonstrates how to compute good indicators of the field size that can be used for commissioning and QA purposes. Methods The proposal is to use profile inflection points as the beam profile characteristic points. The comparison of distances between inflection…

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