0000000000482717

AUTHOR

Massimiliano Curatolo

showing 2 related works from this author

Brain Modulation by Electric Currents in Fibromyalgia: A Structured Review on Non-invasive Approach With Transcranial Electrical Stimulation

2018

Fibromyalgia syndrome (FMS) is a complex disorder where widespread musculoskeletal pain is associated with many heterogenous symptoms ranging from affective disturbances to cognitive dysfunction and central fatigue. FMS is currently underdiagnosed and often very poorly responsive to pharmacological treatment. Pathophysiology of the disease remains still obscure even if in the last years fine structural and functional cerebral abnormalities have been identified, principally by neurophysiological and imaging studies delineating disfunctions in pain perception, processing and control systems. On such basis, recently, neurostimulation of brain areas involved in mechanism of pain processing and …

non-invasive brain stimulation (NIBS) transcranial electrical stimulation (tES) fibromyalgia (FM) tDCS — transcranial direct current stimulation tRNS (transcranial random noise stimulation)medicine.medical_treatmentStimulationReview050105 experimental psychologylcsh:RC321-57103 medical and health sciencesBehavioral Neuroscience0302 clinical medicinefibromyalgia (FM)Fibromyalgiamedicine0501 psychology and cognitive sciencestranscranial electrical stimulation (tES)Neurostimulationlcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological Psychiatrybusiness.industry05 social sciencesCognitionNeurophysiologymedicine.diseasetRNS (transcranial random noise stimulation)Dorsolateral prefrontal cortexSettore MED/16 - ReumatologiaPsychiatry and Mental healthNeuropsychology and Physiological Psychologymedicine.anatomical_structureNeurologytDCS — transcranial direct current stimulationBrain stimulationSettore MED/26 - NeurologiaPrimary motor cortexbusinessnon-invasive brain stimulation (NIBS)Neuroscience030217 neurology & neurosurgeryNeuroscienceFrontiers in Human Neuroscience
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Combination of intensive cognitive rehabilitation and donepezil therapy in Alzheimer's disease (AD).

2009

Acetylcholinesterase inhibitors (AchEIs) are extensively used in Alzheimer's disease (AD) while reality orientation therapy (ROT) is a cognitive rehabilitation indicated for mentally deteriorated patients. We aimed to evaluate the efficacy of the combination of donepezil with an intensive ROT with active participation of the caregiver. Patients with AD (n=100, mean age 78.4±4.3 years) initiated treatment with donepezil, 5mg/day; 62 of them underwent a 3-week, daily ROT and physical reactivation training with the caregiver (Group A); 38 participants received only donepezil therapy (Group B). All subjects were tested for cognitive and functional abilities at baseline, at the end of the traini…

MaleAgingmedicine.medical_specialtyHealth (social science)Diseasechemistry.chemical_compoundPiperidinesAlzheimer Diseasemental disordersmedicineDementiaHumansDonepezilCognitive rehabilitation therapyDonepezilAgedAged 80 and overPsychiatric Status Rating ScalesAnalysis of VarianceChi-Square DistributionCognitive Behavioral TherapyCognitionmedicine.diseaseAcetylcholinesteraseActive participationTreatment OutcomechemistryIndansPhysical therapyFemaleCholinesterase InhibitorsGeriatrics and GerontologyTraining programPsychologyGerontologymedicine.drugArchives of gerontology and geriatrics
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