0000000000482960

AUTHOR

Dohan Anthony

0000-0002-8732-5603

showing 2 related works from this author

Early evaluation using a radiomic signature of unresectable hepatic metastases to predict outcome in patients with colorectal cancer treated with FOL…

2020

PurposeThe objective of this study was to build and validate a radiomic signature to predict early a poor outcome using baseline and 2-month evaluation CT and to compare it to the RECIST1·1 and morphological criteria defined by changes in homogeneity and borders.MethodsThis study is an ancillary study from the PRODIGE-9 multicentre prospective study for which 491 patients with metastatic colorectal cancer (mCRC) treated by 5-fluorouracil, leucovorin and irinotecan (FOLFIRI) and bevacizumab had been analysed. In 230 patients, computed texture analysis was performed on the dominant liver lesion (DLL) at baseline and 2 months after chemotherapy. RECIST1·1 evaluation was performed at 6 months. …

MaleOncologyColorectal cancermedicine.medical_treatmentLeucovorinKaplan-Meier Estimate030218 nuclear medicine & medical imagingMESH: Camptothecin / administration & dosage; Camptothecin / analogs & derivatives; Colorectal Neoplasms / drug therapy; Colorectal Neoplasms / pathology; Computational Biology; Female0302 clinical medicineAntineoplastic Combined Chemotherapy ProtocolsProspective StudiesProspective cohort studyAged 80 and overLiver NeoplasmsGastroenterologyMESH: Radiographic Image Interpretation Computer-Assisted; Response Evaluation Criteria in Solid Tumors; Survival Rate;Tomography X-Ray ComputedMiddle AgedBevacizumabSurvival Rate030220 oncology & carcinogenesisCohortFOLFIRIRadiographic Image Interpretation Computer-AssistedFemaleFluorouracilColorectal NeoplasmsClinical decision makingmedicine.drugAdultmedicine.medical_specialtyBevacizumab[SDV.CAN]Life Sciences [q-bio]/CancerMESH: Fluorouracil / administration & dosage; Humans; Kaplan-Meier Estimate; Leucovorin / administration & dosage; Liver Neoplasms / diagnostic imagingComputerised image analysis03 medical and health sciencesColorectal metastasesMESH: Adult; Aged 80 and over; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Bevacizumab / administration & dosage; Camptothecin / administration & dosagePredictive Value of TestsInternal medicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingmedicineHumansChemotherapyResponse Evaluation Criteria in Solid TumorsMESH: Liver Neoplasms / secondary; Male; Middle Aged; Predictive Value of Tests; Prospective StudiesAgedChemotherapybusiness.industryComputational Biology[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterologymedicine.diseaseColorectal cancerLog-rank testIrinotecanCamptothecinTomography X-Ray ComputedbusinessGut
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Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study

2021

Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231…

MaleVascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERinfectious diseases0302 clinical medicine030202 anesthesiologyAnesthesiologyCirugía80 and overProspective StudiesYoung adultChildLungAged 80 and overCOVID-19 ; delay ; SARS-CoV-2 ; surgery ; timingSARS‐CoV‐2 infectionOperativeChild PreschoolPneumonia & InfluenzaInfectionCohort studyHumanmedicine.medical_specialtydelayClinical SciencesSars-cov-2GlobalSurg CollaborativeSettore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE03 medical and health sciencesClinical ResearchAnesthesiologyBiodefenseCorrespondence617HumansPULMONARY COMPLICATIONSCRIANÇAS EM IDADE PRÉ-ESCOLARAgedScience & TechnologyCirurgiaPreventionCOVID-19; SARS-CoV-2; delay; surgery; timingInfantOdds ratioPneumoniaProspective StudieClinical research/dk/atira/pure/core/keywords/uob_covid19SurgeryHuman medicine610 Medizin und Gesundheit1109 NeurosciencesInternationalitySettore MED/29 - CHIRURGIA MAXILLOFACCIALESettore MED/18 - CHIRURGIA GENERALECOVID-19; delay; SARS-CoV-2; surgery; timing; Adolescent; Adult; Aged; Aged 80 and over; Child; Child Preschool; Cohort Studies; Female; Humans; Infant; Male; Middle Aged; Prospective Studies; SARS-CoV-2; Surgical Procedures Operative; Time; Young Adult; COVID-19; Internationality; Practice Guidelines as TopicgastroenterologyCohort StudiessurgeryMedicine and Health Sciencestiming030212 general & internal medicineProspective cohort studyMortality rateCOVID-19; delay; SARS-CoV-2; surgery; timingCovid19Middle AgedInfectious DiseasesSurgical Procedures OperativePractice Guidelines as TopicFemalePatient Safetymedicine.symptom6.4 SurgeryLife Sciences & BiomedicineAdult61Adolescent610 Medicine & healthCOVID-19 SARS-CoV-2 delay surgery timingAsymptomaticNOCOVIDSurg CollaborativeTimeVaccine RelatedYoung AdultAll institutes and research themes of the Radboud University Medical CentermedicineMortalitatddc:610MortalityPreschoolLS7_4Surgical Proceduresbusiness.industrySARS-CoV-2NeurosciencesEvaluation of treatments and therapeutic interventionsCOVID-191103 Clinical Sciences3126 Surgery anesthesiology intensive care radiologySurgeryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Anesthesiology and Pain MedicineEmerging Infectious DiseasesGood Health and Well BeingMortalidadCohort Studiebusiness
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