0000000000490525

AUTHOR

Michael Larbig

showing 2 related works from this author

Disease control and treatment pathways of asthma patients after initiating ICS/LABA

2019

Introduction: GINA guidelines recommend medium dose (MED) and high dose (HD) ICS/LABA as the preferred controller for step 4 asthma patients and clinicians should consider step up/down based on their patients’ asthma control. Limited data is available on how step 4 patients respond to ICS/LABA and how they step up/down in clinical practice. Methods: We conducted a retrospective cohort study using UK Clinical Practice Research Datalink to assess control status of asthma patients in one year after initiating a MED or HD ICS/LABA between 2007 and 2015, and examined their treatment pathways within one year after the treatment initiation. Results: 29,229 and 16, 575 patients initiated MED and HD…

medicine.medical_specialtybiologyExacerbationbusiness.industryOffice visitsRetrospective cohort studyLamamedicine.diseasebiology.organism_classificationDisease controlMedication possession ratioInternal medicineIcs labamedicinebusinesshormones hormone substitutes and hormone antagonistsAsthmaAirway pharmacology and treatment
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One-year follow up of asthmatic patients newly initiated on treatment with medium- or high-dose inhaled corticosteroid-long-acting β2-agonist in UK p…

2020

Abstract Introduction Global Initiative for Asthma (GINA) recommends medium- or high-dose inhaled corticosteroid-long-acting β2-agonist (ICS-LABA) as preferred treatments for patients with moderate-to-severe asthma. Limited data is available on how step 4/5 patients respond to ICS-LABA and how they step up/down in clinical practice. Methods This retrospective cohort study assessed the characteristics, control status, treatment pathways, and healthcare resource utilization in patients with asthma during one year after initiating medium- or high-dose ICS-LABA. Data from the United Kingdom Clinical Practice Research Datalink were analysed between January 01, 2006 and February 28, 2016. Results…

Pulmonary and Respiratory Medicinemedicine.medical_specialtybiologymedicine.drug_classLeukotriene receptorbusiness.industryAntagonistMuscarinic antagonistRetrospective cohort studyLamamedicine.diseasebiology.organism_classification03 medical and health sciences0302 clinical medicine030228 respiratory systemInternal medicineCohortmedicineCorticosteroid030212 general & internal medicinebusinessAsthmamedicine.drugRespiratory Medicine
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