YOLK SAC deL TESTICOLO. Raro caso con metastasi retroperitoneale

Gli Autori riportano un caso di tumore primitivo del testicolo (Yolk Sac Tumor) e metastasi gigante retroperitoneale e sindrome virilizzante associata

Acute and chronic hepatitis in childhood leukemia: a multicentric study from the Italian Pediatric Cooperative Group for Therapy of Acute Leukemia (AIL-AIEOP).

The incidence of acute and chronic liver damage and its relation to hepatitis B virus (HBV) infection was evaluated in 164 consecutive children with acute leukemia seen in ten Italian hemato-pediatric units. Thirteen out of 164 children (7.9%) had acute hepatitis (AH) during treatment, while 8/90 (8.8%) showed an acute exacerbation of liver damage within 6 months after therapy withdrawal. Seven of the 13 children with AH while on therapy were HBsAg positive. In 12/13 cases, liver disease progressed to chronicity. Five of eight children who developed AH after completion of treatment were HBsAg positive. Eighty-nine patients (54.2%) developed biochemical evidence of chronic hepatitis during t…

Pain in paediatric hospital units

TUMORI a CELLULE GERMINALIin ETA' PEDIATRICA: FATTORI PROGNOSTICI del PROTOCOLLO AIEOP TCG 91.

CIRCA IL 20% DEI PAZIENTI CON TUMORI A CELLULE GERMINALI (tcg) SONO RESISTENTI AL TRATTAMENTO. GLI aUTORI HANNO EFFETTUATO UNO STUDIO POLICENTRICO AL FINE DI RILEVARE CORRELAZIONI TRA PARAMETRI CLINOCO/LABORATORISTICI E LA PROGNOSI

GERM CELL TUMOURS IN CHILDREN- A Report of 84 Cases

In January 1991 a Protocol for diagnosis and treatment of Germ Cell Tumours (GCT) in children was activated in 15 Italian Paediatric Centres.

I TUMORI A CELLULE GERMINALI: CLINICA E TERAPIA

Gli studi embriologici ed anatomopatologici hanno chiarito le origini dei Tumori a cellule germinali e di classificarli in diversi tipi istologici, benigni e maligni, riconducibili al momento differenziativo durante il quale la cellula primordiale viene colpita da un imput o proliferativo o neoplastico. Viene esaminato ogni aspetto clinico con la migliore forma di terapia.

SURGERY OF GERM CELL TUMORS IN PEDIATRIC AGE: Preliminart data od TCG)! series of the New Italian Protocol

The authors report the preliminary data of the case studies of the new National Protocol TGC91 and examine the role of surgery in the treatment of these neoplasms

FAILURE of TERATMENT in CHILDHOOD EXTRACRANIAL and EXTRATESTICULAR MALIGNANT GERM CELL TUMOURS (mgct)

Platinum based chemptherapy improves the cure rate of patients with MGCT to over 80 poer cent, but tumour recurrence is associated with an unfavourable prognosis. We sought to identify factors predicitive of poor outcome following relapse.

IL TUMORE DI ASKIN. Descrizione di un caso clinico e Revisione della Letteratura

The Authors report a case of Askin's tumor, considered a peripheral Neuroectodermal tumor (PNET) and the correct treatment on diagnosi and therapy is reported

TUMORI A CELLULE GERMINALI IN ETA' PEDIATRICA. RISULTATI DEL PROTOCOLLO AIEOP "TG-91".

Gli Autori riportano i risultati del Protocollo AIEOP-91 presentando igli 88 casi registrati in 15 Centro AIEOP dal gGennaio 1991 al Dicembre 193

TERATOMI SACRO-COCCIGEI: Osservazioni su 25 casi

Gli Autori presentano i dati relativi ad uno studio retrospettivo su 25 casi di Teratoma sacrococcigeo, osservati tra il 1980 ed il 1988.

MALIGNANT NON-SEMINOMATOUS GERM CELL TUMORS (MNSGCT) IN CHILDREN: Results of a Study of Italian Association Pediatric Oncology (AIEOP).

The authors report the results of the Italian study on the treatment of non-seminomatous germ cell tumors in pediatric age and present the results of the diagnostic and therapeutic process in their experience

MALIGNANT GERM CELL TUMOURS in CHILDHOOD: the Italian Experience

Malignant Germ Cell Tumours (MGCT) account approximately 3% of all malignancies in the paediatric age group. Although many of them are curable, their natural history, staging, systems and optimal treatment still need to be better defined. Tha data of an Italian co-operative study are reported here

YOLK SAC DEL TESTICOLO: Raro Caso con Metastasi Gigante Retroperitoneale

The authors restorate a case of primary testis tumor (Yolk Sac Tumor) and giant retroperitoneal metastasis clinically evident as a voluminous abdominal mass (23 cm) and associated virilizing syndrome. the diagnostic and therapeutic procedure performed is described.

The outcome of Wilms' tumor in infants. Italy 1970-79.

Thirty-four infants under 1 year of age with Wilms’ tumor were diagnosed and treated in 14 Italian pediatric oncology units during 1970-79. The 3-year survival rates decreased with higher group unilateral tumors: 95% in group I Wilms’ tumor, 75% in group II and 20% in group III. The survival rates for children with group I and II Wilms’ tumor were similar for those who were treated with surgery and chemotherapy and those who also received postoperative radiotherapy. During 1975-79 fewer patients with group I Wilms’ tumor received radiotherapy (1 of 11) than during 1970-74 (4 of 6, p < 0.05). All these children are alive at this writing.

GERM CELL TUMORS OF THE TESTIS (tgct) IN CHOLDHOOD. A Review from a National Case Report

Tha Authors report a retrospective Study carried out because of the rarity of Primary Testicular Tumors (PTT) in childhood. The aim was to revise the surgical treatment performed in 60 Pz affected by PTT during a 10 year period.

GERM CELL TUMOURS: A Report of 72 Cases

The Authours report a prospective Study of the diagnosis and treatment of Germ Cell Tumours in children since January 1991.

TUMORI A CELLULE GERMINALI MALIGNI IN ETA’ PEDIATRICA: RISULTATI DEL II STUDIO COOPERATIVO ITALIANO TCG 98

Gli Autori presentano i risultati del Secondo Studio Cooperativo Italiano sui Tumori a Cellulle Germinali Maligni del bambino, esito del Proytocollo Nazionale TCG 98.

I TUMORI A CELLULE GERMINALI IN ETA' PEDIATRICA

Gli Autori presentano il progetto del Protocollo Nazionale di disgnosi e cura dei Tumori a Cellule germinali (TCG) con gli obiettivi di costituire una casistica nazionale, approfondire la storia naturale dei TCG, promuovere un trattametno uniforme nazionale. vengono presentati i primi dati.

IL TERATOMA ED IL CHIRURGO PEDIATRA. Considerazioni sull'approccio e valutazioni dalla Casistica Nazionale "TCG 91".

Germ Cell Tumors (GCT) are rare in childhood, accounting for 2-4% of all solid neoplasms. Teratoma is the most frequent histological type (50%) of GCT and the most important neonatal tumors.. Authors analyze the results of the first Italian Multicentric Cooperative Study on GCTs in childhood (TCG 91). The role of surgical radical excision of the mass with thw coccyx in sacrococcygeal forms is streassed.

LA CHIRURGIA DEI TUMORI GERMINALI NELL'ETA' PEDIATRICA

Gli Autori eseminano tutti gli aspetti del ruolo della chirurgia nel trattamento di queste neoplasie, valutandone le applicazioni per tipo di tumore, benigno o maligno, e per sede interessata.

EXTRAGONADAL GERM CELL TUMORS: Results of AIEOP TCG 91/98 Protocols

The aim of the Study: To analyze the outcome of patirnts with extragonadal (eg) GCT teated with TCG 91/98 Protocols. 45 pts were enrolled: 34 were females, 11 males; median age 17 months (range: 1-137 months)

THE ROLE OF SURGERY (s) IN THE TREATMENT OF GERM CELL TUMORS (GCT) IN CHILDHOOD. A Report from an Italian Multi-Istitutional Study (TCG-91)

GCT account for about 3% of all solidi Neoplasms in children. Because of the confusion as to their classification, diagnostic apporoach and treatment, a multi-istitutional study was carried and a National Protocol for Diagnosis and treatment of CGT (TCG-91), approved by AIEOP, straded in January 1991.

TERATOMA IMMATURO EXTRACRANICO: Risultati dello Studio Cooperativo AIEOP "TCG-91".

I Teratomi Immatuti sono tumori costituiti da tessuto non maligno ma con potenzialità evolutiva maligna. Gli Autori presentano i dati dello Studio Cooperativo "TCG-91".

PLEUROPULMONARY BLASTOMA: A DIFFERENTIAL DIAGNOSIS OF CHRONIC COUGH. LONG TERM SURVIVALAFTER MULTIMODAL AGGRESSIVE THERAPY

ITAL J PEDIATR 2006;32:122-125 CASE REPORT CASO CLINICO Pleuropulmonary blastoma: a differential diagnosis of chronic cough. Long-term survival after multimodal aggressive therapy Blastoma pleuro-polmonare: rara diagnosi differenziale da tosse cronica. Remissione a lungo termine dopo aggressiva terapia multimodale P. D''ANGELO, V. MANZO*, S. VENEZIA*, R. ALAGGIO", E SIRACUSA*, M. LO CURTO* Unità Operativa di Oncoematologia Pediatrica, Ospedale dei Bambini " G . Di Cristina", Palermo; * Dipartimento Materno Infantile, Università di Palermo; ** Istituto di Anatomia Patologica, Università di Padova Summary Pleuropulmonary blastoma (PPB) in childhood is a rare clinicopathologic entity distinct …

Leukemic ophthalmopathy: a report of 21 pediatric cases.

A multicentric retrospective study on leukemic ophthalmopathy (LO) is reported. It includes 21 patients, 16 males and 5 females, with acute leukemia (AL) observed in 10 SIOP centers. LO developed in three patients at the time of diagnosis of AL; five patients were in first complete remission (three off therapy); four patients were in second or third remission; and nine were in combined relapse. Most frequent symptoms were blurred vision, photophobia, and ocular pain. Two patients with acute nonlymphoblastic leukemia died before treatment; another underwent bone marrow transplantation; one patient with B-cell acute lymphoblastic leukemia (B-ALL) treated with chemotherapy and radiotherapy die…

SURGERY IN MALIGNANT GERM CELL TUMORS OF CHILDHOOD. RESULTS OF THE SECOND ITALIAN COOPERATIVE STUDY TCG 98

Analysis of treatment and results of the patientsenrolled in the Italian TCG-98 Study, still open and comparison of data with those of the previous Studt TCG-91

Teratoma with a malignant somatic component in pediatric patients: The Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) experience

BACKGROUND: Teratoma with a malignant somatic component (TMSC) is rare but described in adults, whereas information on pediatric presentation is sparse. PROCEDURE: The Associazione Italiana Ematologia Oncologia Pediatrica identified 14 cases of TMSC. Clinical files and pathology specimens were reviewed. RESULTS: The series (9 female, 5 male) showed the following disease: testis (2), sacrococcygeal (3), ovary (3), retroperitoneum (3), mediastinum (2), and foot soft tissue (1). Distribution of the somatic component was: carcinoma (4), pancreatic neuroendocrine tumor (1), neuroblastoma (3), rhabdomyosarcoma (3), rhabdomyosarcoma plus liposarcoma, chondrosarcoma, neurogenic sarcoma (1), chondro…