0000000000496389

AUTHOR

Roberto Vicentini

showing 2 related works from this author

<p>Weekly alternate intensive regimen FIrB/FOx in metastatic colorectal cancer patients: an update from clinical practice</p>

2019

Background Several trials evaluated the role of intensive regimens, made of triplet chemotherapies plus bevacizumab, as first-line treatment for patients with metastatic colorectal cancer (mCRC). We previously reported, in a Phase II prospective study, the efficacy and the tolerability of FIrB/FOx regimen, reporting interesting results in terms of received dose intensities (rDIs) and safety. Methods We reported a retrospective update of 85 patients treated with FIrB/FOx, an intensive regimen of 5-fluorouracil, bevacizumab, and weekly alternate irinotecan and oxaliplatin, to confirm its feasibility in "real life". Subgroup analyses were performed, particularly among patients treated with sta…

0301 basic medicineOncologymedicine.medical_specialtyBevacizumabPerformance statusbusiness.industryNeutropeniamedicine.diseaseOxaliplatinIrinotecan03 medical and health sciencesRegimen030104 developmental biology0302 clinical medicineOncologyTolerability030220 oncology & carcinogenesisInternal medicinemedicinePharmacology (medical)businessProspective cohort studymedicine.drugOncoTargets and Therapy
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Dose-finding study of oxaliplatin associated to capecitabinebased preoperative chemoradiotherapy in locally advanced rectal cancer

2018

// Gemma Bruera 1, 2 , Mario Di Staso 3 , Pierluigi Bonfili 3 , Antonio Galvano 4 , Rosa Manetta 5 , Gino Coletti 6 , Roberto Vicentini 7 , Stefano Guadagni 2, 8 , Corrado Ficorella 2, 9 , Ernesto Di Cesare 2, 3 , Antonio Russo 4 and Enrico Ricevuto 1, 2 1 Oncology Territorial Care, S. Salvatore Hospital, Oncology Network ASL1 Abruzzo, University of L'Aquila, L'Aquila, Italy 2 Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy 3 Radiotherapy, S. Salvatore Hospital, Oncology Network ASL1 Abruzzo, University of L’Aquila, L’Aquila, Italy 4 Medical Oncology, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo,…

medicine.medical_specialtyCapecitabine; Chemoradiotherapy; Dose-finding; Locally advanced rectal cancer; Oxaliplatin; OncologyColorectal cancerSettore MED/06 - Oncologia Medicamedicine.medical_treatmentRectumchemoradiotherapyCapecitabine03 medical and health sciences0302 clinical medicinelocally advanced rectal cancermedicineMucositisbusiness.industryGeneral surgerycapecitabineoxaliplatinmedicine.diseaseOxaliplatinRadiation therapyRegimenmedicine.anatomical_structureOncology030220 oncology & carcinogenesisdose-findingClinical Research Paperbusiness030217 neurology & neurosurgeryChemoradiotherapymedicine.drug
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