0000000000496918

AUTHOR

Barbara Jarząb

0000-0001-9811-9584

showing 2 related works from this author

European perspective on the 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroi…

2018

The American Thyroid Association (ATA) management guidelines for patients with thyroid nodules and differentiated thyroid cancer (DTC) are highly influential practice recommendations. The latest revision appeared in 2015 ("ATA 2015"). These guidelines were developed predominantly by North American experts. European experts frequently have different perspectives, given epidemiological, technological/methodological, practice organization, and medicolegal differences between the respective regions.Divergent viewpoints were the focus of an invited symposium organized by the European Association of Nuclear Medicine involving 17 European thyroidologists, four ATA Guidelines Taskforce members, and…

AdultThyroid nodulesendocrine systemmedicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and MetabolismMedizinThyroid Gland030209 endocrinology & metabolismrisk stratificationHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciences0302 clinical medicineEndocrinologyAll institutes and research themes of the Radboud University Medical CenterInternal medicineHumansMedicineThyroid NeoplasmsThyroid NoduleguidelinesDisease management (health)differentiated thyroid cancer (DTC)Thyroid cancerAdult patientsbusiness.industrythyroid nodulesPerspective (graphical)Thyroidmedicine.diseaseUnited Statesdifferentiated thyroid cancer (DTC); disease management; guidelines; pathology; risk stratification; thyroid nodules; Endocrinology Diabetes and Metabolism; EndocrinologyEuropeDiabetes and Metabolismmedicine.anatomical_structuredisease management030220 oncology & carcinogenesisPractice Guidelines as TopicRisk stratificationpathologybusiness
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A two miRNA classifier differentiates follicular thyroid carcinomas from follicular thyroid adenomas.

2015

The inherent diagnostic limitations of thyroid fine needle aspiration (FNA), especially in the "indeterminate" category, can be partially overcome by molecular analyses. We aimed at the identification of miRNAs that could be used to improve the discrimination of indeterminate FNAs. miRNA expression profiling was performed for 17 follicular carcinomas (FTCs) and 8 follicular adenomas (FAs). The microarray results underwent cross-comparison using three additional microarray data sets. Candidate miRNAs were validated by qPCR in an independent set of 32 FTCs and 46 FAs. Sixty-eight differentially expressed miRNAs were identified. Thirteen miRNAs could be confirmed by cross comparison. A two-miR…

Thyroid nodulesMaleMicroarrayThyroid Neoplasms/classificationBiologyBioinformaticsClassifierMicroRNAs/biosynthesisBiochemistryFollicular thyroid cancerThyroid carcinomaAdenocarcinoma Follicular/classificationEndocrinologyAdenocarcinoma FollicularDatabases GeneticmedicineHumansRNA NeoplasmThyroid NeoplasmsFollicular thyroid cancerMolecular Biologymedicine.diagnostic_testMicroarray analysis techniquesThyroidmedicine.diseaseGene Expression Regulation NeoplasticMicroRNAsFine-needle aspirationmedicine.anatomical_structureCancer researchFemaleFollicular thyroid adenomaIndeterminateRNA Neoplasm/biosynthesisMolecular and cellular endocrinology
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